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Accepted for/Published in: JMIR Research Protocols

Date Submitted: Dec 8, 2022
Open Peer Review Period: Dec 8, 2022 - Feb 2, 2023
Date Accepted: Feb 8, 2023
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

A Multicomponent Intervention to Train and Support Family Medicine Providers to Promote Pre-exposure Prophylaxis (PrEP) for Adolescent Girls and Young Women in the Deep South: Protocol for the PrEP-Pro Study

Isehunwa OO, Hill SV, Menninger AT, Hubner B, Krakower D, Long DM, Clement ME, Wagoner NV, Lanzi RG, Simpson T, Elopre L, Matthews LT

A Multicomponent Intervention to Train and Support Family Medicine Providers to Promote Pre-exposure Prophylaxis (PrEP) for Adolescent Girls and Young Women in the Deep South: Protocol for the PrEP-Pro Study

JMIR Res Protoc 2023;12:e44908

DOI: 10.2196/44908

PMID: 36943364

PMCID: 10131664

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Protocol for a Multi-component Intervention to Train and Support Family Medicine Providers to Promote PrEP for Adolescent Girls and Young Women in the Deep South: The PrEP-Pro Study

  • Oluwaseyi O. Isehunwa; 
  • Samantha V. Hill; 
  • Alex Tobias Menninger; 
  • Brook Hubner; 
  • Doug Krakower; 
  • Dustin M. Long; 
  • Meredith E. Clement; 
  • Nicholas Van Wagoner; 
  • Robin Gaines Lanzi; 
  • Tina Simpson; 
  • Latesha Elopre; 
  • Lynn T. Matthews

ABSTRACT

Background:

Pre-exposure prophylaxis (PrEP) is widely recognized as a highly effective biomedical prevention intervention and a major strategy for reducing the burden of HIV in the United States. However, PrEP provision and uptake remain low compared to estimated need and in ways that may exacerbate HIV disparities among Black adolescent girls and young women (AGYW) in the US South.

Objective:

This protocol paper describes the “PrEP Pro” intervention, a multi-component intervention to train and support family medicine (FM) trainees to promote PrEP for AGYW in Alabama.

Methods:

The PrEP Pro intervention consists of three main components guided by the Capability-Opportunity-Motivation-Behavior (COM-B) model for behavioral change and the Consolidated Framework for Implementation Research (CFIR): 1) Provider PrEP education, 2) sexual history taking, and 3) PrEP Champions. In phase 1, we will adapt content to train FM residents on HIV epidemiology and PrEP and develop implementation strategies including provider-facing tools and client-facing educational materials. In phase 2, we will pre-test then pilot-test the initially adapted PrEP-Pro intervention with family medicine trainees. The primary outcomes to be assessed include PrEP-Pro acceptability and feasibility. Secondary outcomes will also be assessed including PrEP knowledge, sexual history taking attitudes and practices, PrEP prescriptions among AGYW encounters, and STI and HIV testing among AGYW encounters. The results of this study will inform a hybrid effectiveness-implementation trial

Results:

This study has been approved by the Institutional Review Board of the University of Alabama at Birmingham. Findings from this study will be presented locally to the community advisory board members and disseminated to practices, state health officials, and other key stakeholders. Also, study findings will be presented at local and national conference meetings and submitted to peer-reviewed journals for publication.

Conclusions:

The PrEP-Pro intervention is a multi-component intervention to train FM residents across Alabama on sexual history taking, PrEP provision for AGYW, and support practice-based PrEP Champions. It is expected that the PrEP-Pro intervention will lead to an increase in PrEP prescriptions to AGYW and an expansion of comprehensive sexual and reproductive health care for AGYW in rural and urban Alabama.


 Citation

Please cite as:

Isehunwa OO, Hill SV, Menninger AT, Hubner B, Krakower D, Long DM, Clement ME, Wagoner NV, Lanzi RG, Simpson T, Elopre L, Matthews LT

A Multicomponent Intervention to Train and Support Family Medicine Providers to Promote Pre-exposure Prophylaxis (PrEP) for Adolescent Girls and Young Women in the Deep South: Protocol for the PrEP-Pro Study

JMIR Res Protoc 2023;12:e44908

DOI: 10.2196/44908

PMID: 36943364

PMCID: 10131664

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