Accepted for/Published in: JMIR Research Protocols
Date Submitted: Dec 5, 2022
Date Accepted: Apr 19, 2023
Fertility Preserving Techniques in Neuro-Oncology Patients: A Systematic Review Protocol
ABSTRACT
Background:
CNS Cancer survivorship is rapidly improving and the awareness of the importance of fertility preservation techniques is increasing. Currently, a range of techniques are available however, oncologists are hesitant to refer patients to a reproductive specialist.
Objective:
The primary aim of the proposed systematic review is to assess the best evidence for fertility preservation techniques used in patients with CNS cancers. It also aims to evaluate outcomes relating to their success and complications.
Methods:
This protocol is produced in adherence with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Protocols. Electronic databases will be systematically searched to identify studies that meet our eligibility criteria. From the included studies, data will be extracted and synthesized using a narrative approach and summarized in tables. The quality of the included studies will be assessed using the National Heart, Lung and Blood Institute risk-of-bias tool for any type of studies
Results:
This systematic review is expected to be completed by the end of 2023 and the results published in a peer-reviewed journal and on PROSPERO.
Conclusions:
The proposed systematic review will summarize the fertility preservation techniques available for patients with CNS cancers. Results from this review will provide an evidence base for referring patients with CNS cancers for fertility preservation treatments.
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Copyright
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