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Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Dec 4, 2022
Date Accepted: Apr 28, 2023
Date Submitted to PubMed: May 1, 2023

The final, peer-reviewed published version of this preprint can be found here:

Evaluating Listening Performance for COVID-19 Detection by Clinicians and Machine Learning: Comparative Study

Han J, Montagna M, Grammenos A, Xia T, Bondareva E, Siegele-Brown C, Chauhan J, Dang T, Spathis D, Floto A, Cicuta P, Mascolo C

Evaluating Listening Performance for COVID-19 Detection by Clinicians and Machine Learning: Comparative Study

J Med Internet Res 2023;25:e44804

DOI: 10.2196/44804

PMID: 37126593

PMCID: 10206619

Comparing Listening Performance for COVID-19 Detection between Clinicians and Machine Learning: A Comparative Study

  • Jing Han; 
  • Marco Montagna; 
  • Andreas Grammenos; 
  • Tong Xia; 
  • Erika Bondareva; 
  • Chloë Siegele-Brown; 
  • Jagmohan Chauhan; 
  • Ting Dang; 
  • Dimitris Spathis; 
  • Andres Floto; 
  • Pietro Cicuta; 
  • Cecilia Mascolo

ABSTRACT

Background:

To date, performance comparisons between men and machines have been performed in many health domains. Yet, machine learning models and human performance comparisons in audio-based respiratory diagnosis remain largely unexplored.

Objective:

The primary objective of this study is to compare human clinicians and a machine learning model in predicting COVID-19 from respiratory sound recordings.

Methods:

In this study, we compare human clinicians and a machine learning model in predicting COVID-19 from respiratory sound recordings. Prediction performance on 24 audio samples (12 tested positive) made by 36 clinicians with experience in treating COVID-19 or other respiratory illnesses is compared with predictions made by a machine learning model trained on 1,162 samples. We also investigated whether combining the predictions of the model and human experts could further enhance the performance, in terms of both accuracy and confidence.

Results:

The machine learning model outperformed the clinicians, yielding a sensitivity of 0.75 and a specificity of 0.83. Integrating clinicians’ and model’s predictions, however, could enhance performance further, achieving a sensitivity of 0.83 and a specificity of 0.92.

Conclusions:

Our findings suggest that the clinicians and the machine learning model could make better clinical decisions via a cooperative approach and achieve higher confidence in audio-based respiratory diagnosis.


 Citation

Please cite as:

Han J, Montagna M, Grammenos A, Xia T, Bondareva E, Siegele-Brown C, Chauhan J, Dang T, Spathis D, Floto A, Cicuta P, Mascolo C

Evaluating Listening Performance for COVID-19 Detection by Clinicians and Machine Learning: Comparative Study

J Med Internet Res 2023;25:e44804

DOI: 10.2196/44804

PMID: 37126593

PMCID: 10206619

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