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Accepted for/Published in: JMIR Formative Research

Date Submitted: Nov 2, 2022
Open Peer Review Period: Oct 31, 2022 - Dec 26, 2022
Date Accepted: Apr 30, 2023
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Development and Integration of Machine Learning Algorithm to Identify Peripheral Arterial Disease: Multistakeholder Qualitative Study

Wang SM, Hogg HJ, Sangvai D, Patel MR, Weissler EH, Kellogg KC, Ratliff W, Balu S, Sendak M

Development and Integration of Machine Learning Algorithm to Identify Peripheral Arterial Disease: Multistakeholder Qualitative Study

JMIR Form Res 2023;7:e43963

DOI: 10.2196/43963

PMID: 37733427

PMCID: 10557008

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

“The Actual Model Itself…It’s Actually Not That Important”: A Multi-Stakeholder Qualitative Analysis of a Machine Learning-Algorithm Integration

  • Sabrina M. Wang; 
  • H.D. Jeffry Hogg; 
  • Devdutta Sangvai; 
  • Manesh R. Patel; 
  • E. Hope Weissler; 
  • Katherine C. Kellogg; 
  • William Ratliff; 
  • Suresh Balu; 
  • Mark Sendak

ABSTRACT

Background:

Machine-learning (ML) driven computerized decision support (CDS) continues to draw wide interest and investment as a means of improving care quality and value, despite mixed real-world implementation outcomes.

Objective:

This study aims to explore barriers to and facilitators of the integration of a peripheral arterial disease (PAD) identification algorithm to implement timely guideline-based care.

Methods:

Twelve semi-structured interviews were completed with individuals from three stakeholder groups during the first four weeks of integration of a ML CDS-enabled workflow in which an interdisciplinary team used the ML-driven CDS to identify patients with PAD, develop a recommended action plan, and send this recommendation to the patient’s primary care provider (PCP). Pseudonymized transcripts were coded and thematic analysis was completed by a multidisciplinary research team.

Results:

Three themes were identified: Facilitators of translating in-silico performance to real-world efficacy, Organizational and data structure barriers to clinical impact, and Potential barriers to advancing equity. Success criteria for each stakeholder group were also characterized to better understand how teams work together to integrate ML-driven CDS.

Conclusions:

Longitudinal multi-stakeholder engagement in the development and integration of ML-driven CDS supports effective translation into real-world care. This more holistic perspective also permits more effective detection of context-driven healthcare inequities, which are uncovered or exacerbated through ML-driven CDS integration. Many of the solutions to these inequities lie outside the scope of ML and require coordinated systematic solutions for mitigation. Clinical Trial: None.


 Citation

Please cite as:

Wang SM, Hogg HJ, Sangvai D, Patel MR, Weissler EH, Kellogg KC, Ratliff W, Balu S, Sendak M

Development and Integration of Machine Learning Algorithm to Identify Peripheral Arterial Disease: Multistakeholder Qualitative Study

JMIR Form Res 2023;7:e43963

DOI: 10.2196/43963

PMID: 37733427

PMCID: 10557008

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