Accepted for/Published in: JMIR Public Health and Surveillance
Date Submitted: Oct 11, 2022
Date Accepted: Mar 18, 2023
Disease Burden and Accumulation of Multimorbidity of Non-communicable Diseases in Henan Rural Population: A Cross-Sectional Study
ABSTRACT
Background:
Multimorbidity causes significant disease and economic burdens on individuals and the healthcare system.
Objective:
This study aims to explore the disease burden of multimorbidity and the potential correlations among chronic non-communicable diseases (NCDs) in a Henan rural population.
Methods:
A cross-sectional analysis was performed at baseline of the Henan Rural Cohort Study. Multimorbidity was defined as the simultaneous occurrence of at least two NCDs in a participant. This study examined the multimorbidity pattern of six NCDs, including hypertension, dyslipidemia, type 2 diabetes mellitus (T2DM), coronary heart disease (CHD), stroke, and hyperuricemia.
Results:
From July 2015 to September 2017, 38,807 participants (aged 18-79 years, 15,354 men and 23,453 women) were included in this study. The overall population prevalence of multimorbidity was 28.1% (10,899/38,807), and the multimorbidity of hypertension and dyslipidemia was the most common (8.1%, 3,153/38,807). Aging, higher BMI, and unfavourable lifestyles were significantly associated with a higher risk of multimorbidity (multinomial logistic regression, all P<.05). Analysis of the mean age at diagnosis suggested a cascade of interrelated NCDs and their accumulation over age. Compared with participants without two conditional NCDs, participants with one conditional NCD would have higher odds of another NCD (1.2-2.5, all P<.05), and those with two conditional NCDs would elevate the odds of the third NCD to 1.4- 3.5 (binary logistic regression, all P<.05).
Conclusions:
Our findings indicate a plausible tendency for coexistence and accumulation of NCDs in a Henan rural population. Early prevention of multimorbidity is essential to reduce the NCD burden in the rural population.
Citation
Request queued. Please wait while the file is being generated. It may take some time.
Copyright
© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.