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Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Oct 7, 2022
Open Peer Review Period: Oct 7, 2022 - Dec 2, 2022
Date Accepted: Jan 31, 2023
Date Submitted to PubMed: Jan 31, 2023
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Vickybot, a Chatbot for Anxiety-Depressive Symptoms and Work-Related Burnout in Primary Care and Health Care Professionals: Development, Feasibility, and Potential Effectiveness Studies

Anmella G, Sanabra M, Primé-Tous M, Segú X, Cavero M, Morilla I, Ruiz V, Grande I, Mas A, Martín-Villalba I, Caballo A, Esteva JP, Rodríguez-Rey A, Piazza F, Valdesoiro FJ, Rodriguez-Torrella C, Espinosa M, Sorroche C, Virgili G, Ruiz A, Solanes A, Radua J, Also MA, Sant E, Murgui S, Sans-Corrales M, H.Young A, Vicens V, Blanch J, Caballeria E, López-Pelayo H, López C, Olivé V, Pujol L, Quesada S, Solé B, Martínez-Aran A, Torrent C, Guarch J, Navinés R, Murru A, Fico G, De prisco M, Oliva V, Pio C, Amoretti S, Fernández-Canseco M, Villegas M, Vieta E, Hidalgo-Mazzei D

Vickybot, a Chatbot for Anxiety-Depressive Symptoms and Work-Related Burnout in Primary Care and Health Care Professionals: Development, Feasibility, and Potential Effectiveness Studies

J Med Internet Res 2023;25:e43293

DOI: 10.2196/43293

PMID: 36719325

PMCID: 10131622

Vickybot, a chatbot for anxiety-depressive symptoms and work-related burnout in primary care and healthcare professionals: development, feasibility, and potential effectiveness studies.

  • Gerard Anmella; 
  • Miriam Sanabra; 
  • Mireia Primé-Tous; 
  • Xavier Segú; 
  • Myriam Cavero; 
  • Ivette Morilla; 
  • Victoria Ruiz; 
  • Iria Grande; 
  • Ariadna Mas; 
  • Inés Martín-Villalba; 
  • Alejandro Caballo; 
  • Julia-Parisad Esteva; 
  • Arturo Rodríguez-Rey; 
  • Flavia Piazza; 
  • Francisco José Valdesoiro; 
  • Claudia Rodriguez-Torrella; 
  • Marta Espinosa; 
  • Carlota Sorroche; 
  • Giulia Virgili; 
  • Alicia Ruiz; 
  • Aleix Solanes; 
  • Joaquim Radua; 
  • María Antonieta Also; 
  • Elisenda Sant; 
  • Sandra Murgui; 
  • Mireia Sans-Corrales; 
  • Allan H.Young; 
  • Victor Vicens; 
  • Jordi Blanch; 
  • Elsa Caballeria; 
  • Hugo López-Pelayo; 
  • Clara López; 
  • Victoria Olivé; 
  • Laura Pujol; 
  • Sebastiana Quesada; 
  • Brisa Solé; 
  • Anabel Martínez-Aran; 
  • Carla Torrent; 
  • Joana Guarch; 
  • Ricard Navinés; 
  • Andrea Murru; 
  • Giovanna Fico; 
  • Michele De prisco; 
  • Vicenzo Oliva; 
  • Casimiro Pio; 
  • Silvia Amoretti; 
  • María Fernández-Canseco; 
  • Marta Villegas; 
  • Eduard Vieta; 
  • Diego Hidalgo-Mazzei

ABSTRACT

Background:

A significant proportion of people attending Primary Care (PC) have anxiety-depressive symptoms and work-related burnout and there is a lack of resources to attend them. The COVID-19 pandemic has worsened this problem, particularly affecting healthcare workers, and digital tools have been proposed as a workaround. We present the development, feasibility and effectiveness studies of chatbot (Vickybot) aimed at screening, monitoring, and reducing anxiety-depressive symptoms and work-related burnout in PC patients and healthcare workers.

Objective:

Mitigate the growing problem of mental health problems in PC and among healthcare workers by developing a digital decision support platform combining machine-learning severity prediction models (phase 1) with a smartphone-based app for screening, monitoring and delivering evidence-based psychological interventions to people with anxiety and depressive symptoms, and work-related burnout (phase 2). Here we present the results of phase 2: the development, feasibility and effectiveness studies in PC patients and healthcare workers.

Methods:

User-centered development strategies were adopted. Main functions included self-assessments, psychological modules, and emergency alerts. Healthy controls (HCs) tested Vickybot for reliability. (1) Simulation: HCs used Vickybot for 2 weeks to simulate different possible clinical situations and evaluated their experience. (3) Feasibility and effectiveness study: People consulting PC or healthcare workers with mental health problems were offered to use Vickybot for one month. Self-assessments for anxiety (GAD-7) and depression (PHQ-9) symptoms, and work-related burnout (based on the Maslach Burnout Inventory) were administered at baseline and every two weeks. Feasibility was determined based on the combination of both subjective and objective user-engagement Indicators (UEIs). Effectiveness was measured using paired t-tests as the change in self-assessment scores.

Results:

40 HCs tested Vickybot simultaneously, and data was transmitted and registered reliably. (1) Simulation: 17 HCs (73% female; mean age=36.5±9.7) simulated different clinical situations. 98.8% of the expected modules were recommended according to each simulation. Suicidal alerts were correctly activated and received by the research team. (2) Feasibility and effectiveness study: 34 patients (15 from PC and 19 healthcare workers; 77% female; mean age=35.3±10.1) completed the first self-assessments, with 34 (100%) presenting anxiety symptoms, 32 (94%) depressive symptoms, and 22 (64.7%) work-related burnout. Nine (26.5%) patients completed the second self-assessments after 2-weeks of use. No significant differences were found for anxiety [t(8) = 1.000, P = .34] or depressive [t(8) = .40, P = .70] symptoms, but work-related burnout was significantly reduced [t(8) = 2.87, P = .02] between the means of the first and second self-assessments. There was a trend towards higher reduction in anxiety-depressive symptoms and work-related burnout with greater use of the chatbot. Three patients (8.8%) activated the suicide alert, and the research team intervened promptly with successful outcomes. Vickybot showed high subjective-UEIs, but low objective-UEIs (completion, adherence, compliance, and engagement). Feasibility was moderate.

Conclusions:

The chatbot proved to be useful in screening the presence and severity of anxiety and depressive symptoms, in reducing work-related burnout, and in detecting suicidal risk. Subjective perceptions of use contrasted with low objective-use metrics. Our results are promising but suggest the need to adapt and enhance the smartphone-based solution in order to improve engagement. Consensus on how to report UEIs and validate digital solutions, especially for chatbots, are required.


 Citation

Please cite as:

Anmella G, Sanabra M, Primé-Tous M, Segú X, Cavero M, Morilla I, Ruiz V, Grande I, Mas A, Martín-Villalba I, Caballo A, Esteva JP, Rodríguez-Rey A, Piazza F, Valdesoiro FJ, Rodriguez-Torrella C, Espinosa M, Sorroche C, Virgili G, Ruiz A, Solanes A, Radua J, Also MA, Sant E, Murgui S, Sans-Corrales M, H.Young A, Vicens V, Blanch J, Caballeria E, López-Pelayo H, López C, Olivé V, Pujol L, Quesada S, Solé B, Martínez-Aran A, Torrent C, Guarch J, Navinés R, Murru A, Fico G, De prisco M, Oliva V, Pio C, Amoretti S, Fernández-Canseco M, Villegas M, Vieta E, Hidalgo-Mazzei D

Vickybot, a Chatbot for Anxiety-Depressive Symptoms and Work-Related Burnout in Primary Care and Health Care Professionals: Development, Feasibility, and Potential Effectiveness Studies

J Med Internet Res 2023;25:e43293

DOI: 10.2196/43293

PMID: 36719325

PMCID: 10131622

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