Maintenance Notice

Due to necessary scheduled maintenance, the JMIR Publications website will be unavailable from Wednesday, July 01, 2020 at 8:00 PM to 10:00 PM EST. We apologize in advance for any inconvenience this may cause you.

Who will be affected?

Accepted for/Published in: JMIR Research Protocols

Date Submitted: May 6, 2022
Date Accepted: Jan 18, 2023

The final, peer-reviewed published version of this preprint can be found here:

The Vaping and Patterns of e-Cigarette Use Research Study: Protocol for a Web-Based Cohort Study

Hardesty J, Crespi E, Nian Q, Sinamo JK, Breland AB, Eissenberg T, Welding K, Kennedy RD, Cohen JE

The Vaping and Patterns of e-Cigarette Use Research Study: Protocol for a Web-Based Cohort Study

JMIR Res Protoc 2023;12:e38732

DOI: 10.2196/38732

PMID: 36862467

PMCID: 10020901

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

The Vaping and Patterns of E-cigarette use Research Study (VAPER Study): Protocols for an Online Cohort Study

  • Jeffrey Hardesty; 
  • Elizabeth Crespi; 
  • Qinghua Nian; 
  • Joshua K Sinamo; 
  • Alison B Breland; 
  • Thomas Eissenberg; 
  • Kevin Welding; 
  • Ryan David Kennedy; 
  • Joanna E Cohen

ABSTRACT

Background:

3.2% of U.S. adults report using e-cigarettes every day or some days. The Vaping and Patterns of E-cigarette use Research (VAPER) Study is an online longitudinal survey designed to observe patterns in device and liquid use that suggest benefits and unintended consequences of potential e-cigarette regulations. The heterogeneity of the e-cigarette devices and liquids on the market, the customizability of the devices and liquids, and the lack of standardized reporting requirements result in unique measurement challenges. Furthermore, bots and fraudulent survey takers who submit falsified responses are threats to data integrity that require mitigation strategies.

Objective:

To describe the protocols for waves 1-3 of the VAPER Study and discuss recruitment and data processing experiences and lessons learned, including the benefits and limitations of bot- and fraudulent survey taker-related strategies.

Methods:

U.S. adults (21+) who use e-cigarettes five or more days/week are recruited from up to 404 Craigslist catchment areas covering all 50 states. The questionnaire measures and skip logic are designed to accommodate marketplace heterogeneity and user customization (e.g., different skip logic pathways for different device types and customizations). To reduce reliance on self-report data, we also require participants to submit a photo of their device. All data are collected using REDCap. Incentives are US $10 Amazon gift codes delivered by mail to new participants and electronically to returning participants. Those lost to follow-up are replaced. Several strategies are applied to mitigate risk and maximize the odds that participants who receive incentives are not bots and are participants likely in possession of an e-cigarette (e.g., required identity check and photo of a device).

Results:

Three waves of data were collected between 2020-2021 (Wave 1: N=1209; Wave 2: N=1218; Wave 3: N=1254). Retention from Waves 1 to 2 was 52% (628/1209) and 33% (454/1209) of the Wave 1 sample completed all three waves. These data were mostly generalizable to daily e-cigarette users in the United States and post-stratification weights were generated for future analyses.

Conclusions:

Relative to existing e-cigarette cohort studies, this study methodology has some advantages, including efficient recruitment of a lower prevalence population and collection of detailed data relevant to tobacco regulatory science (e.g., device wattage). The online nature of the study requires several bot and fraudulent survey taker-related risk mitigation strategies and these strategies can be time-intensive. When these risks are addressed, online cohort studies can be successful. We will continue to explore methods for maximizing recruitment efficiency, data quality, and participant retention in subsequent waves.


 Citation

Please cite as:

Hardesty J, Crespi E, Nian Q, Sinamo JK, Breland AB, Eissenberg T, Welding K, Kennedy RD, Cohen JE

The Vaping and Patterns of e-Cigarette Use Research Study: Protocol for a Web-Based Cohort Study

JMIR Res Protoc 2023;12:e38732

DOI: 10.2196/38732

PMID: 36862467

PMCID: 10020901

Download PDF


Request queued. Please wait while the file is being generated. It may take some time.

© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.