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Accepted for/Published in: JMIR Research Protocols

Date Submitted: Mar 30, 2022
Open Peer Review Period: Mar 30, 2022 - May 25, 2022
Date Accepted: Aug 6, 2022
Date Submitted to PubMed: Aug 9, 2022
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

The Pragmatic Return to Effective Dental Infection Control Through Triage and Testing (PREDICT) Study: Protocol for a Prospective Clinical Study in the National Dental Practice–Based Research Network

Fredericks-Younger J, Fine DH, Subramanian G, Coker MO, Meyerowitz C, Ragusa P, Allareddy V, McBurnie MA, Funkhouser E, Gennaro ML, Feldman CA

The Pragmatic Return to Effective Dental Infection Control Through Triage and Testing (PREDICT) Study: Protocol for a Prospective Clinical Study in the National Dental Practice–Based Research Network

JMIR Res Protoc 2022;11(8):e38386

DOI: 10.2196/38386

PMID: 35944181

PMCID: 9439378

The Pragmatic Return to Effective Dental Infection Control through Triage and Testing (PREDICT): Protocol for a Prospective Clinical Study in the National Dental Practice-Based Research Network

  • Janine Fredericks-Younger; 
  • Daniel H. Fine; 
  • Gayathri Subramanian; 
  • Modupe O. Coker; 
  • Cyril Meyerowitz; 
  • Patricia Ragusa; 
  • Veerasathpurush Allareddy; 
  • Mary Ann McBurnie; 
  • Ellen Funkhouser; 
  • Maria L. Gennaro; 
  • Cecile A. Feldman

ABSTRACT

Background:

Dental practice has been greatly affected by the COVID-19 pandemic. As SARS-COV-2 infection is transmitted by respiratory fluids, dental practice techniques, which include aerosol-generating procedures, can increase the risk of transmission causing heightened safety concerns for both dental health care workers (DHCWs) and patients. These concerns have resulted in the reduction in patient volume and the available workforce within dental practices across the United States. Standardized methods for COVID-19 triage and testing may lead to increased safety and perceptions of safety for DHCWs and their patients and promote willingness to provide and access oral healthcare services.

Objective:

This study is designed to develop procedures that test the feasibility of enhanced COVID-19 triage and testing in dental offices. It will provide preliminary data to support a larger network-wide study grant application aimed at developing protocols to address safety concerns of patients and DHCWs in a peri-COVID-19 pandemic era.

Methods:

The feasibility study is being conducted in four private dental practices, each of which has a dentist member of the National Dental Practice-Based Research Network. Participants include the DHCWs and patients of the dental practice. Study procedures include completion of COVID-19 triage, completion of COVID-19 testing [Point-of-Care (POC) or laboratory based (LAB) Laboratory (LAB) SARS-CoV-2 viral, antigen and/or antibody tests based on office designation] and administration of perception and attitude surveys for participating DCHWs and patients of the dental practice over a defined study period. The office designation and participant’s role in the practice determines which testing protocol is executed within the office. There are four study groups following four distinct protocols: (1) POC DHCWs, (2) POC Patients, (3) LAB DHCWs, and (4) LAB Patients.

Results:

This work has been peer reviewed and funded by the National Institute of Dental and Craniofacial Research (NIDCR), an institute within the National Institute of Health (NIH). Study protocols commenced in December of 2021 and are expected to end in March 2022 with data analysis to follow.

Conclusions:

The results of this feasibility study will help identify viability and functionality of COVID-19 triage and testing in dental practices and inform a larger network-wide study grant application that develops protocols that address safety concerns of patients and Dental Health Care Workers (DHCWs) in a COVID-19 environment. Clinical Trial: The ClinicalTrials.gov registration is NTC05123742.


 Citation

Please cite as:

Fredericks-Younger J, Fine DH, Subramanian G, Coker MO, Meyerowitz C, Ragusa P, Allareddy V, McBurnie MA, Funkhouser E, Gennaro ML, Feldman CA

The Pragmatic Return to Effective Dental Infection Control Through Triage and Testing (PREDICT) Study: Protocol for a Prospective Clinical Study in the National Dental Practice–Based Research Network

JMIR Res Protoc 2022;11(8):e38386

DOI: 10.2196/38386

PMID: 35944181

PMCID: 9439378

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