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Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Mar 10, 2022
Open Peer Review Period: Mar 9, 2022 - Apr 14, 2022
Date Accepted: Jul 25, 2022
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Digital Health Interventions for Musculoskeletal Pain Conditions: Systematic Review and Meta-analysis of Randomized Controlled Trials

Valentijn PP, Tymchenko L, Jacobson T, Kroman J, Biermann CW, AlMoslemany MA, Arends RY

Digital Health Interventions for Musculoskeletal Pain Conditions: Systematic Review and Meta-analysis of Randomized Controlled Trials

J Med Internet Res 2022;24(9):e37869

DOI: 10.2196/37869

PMID: 36066943

PMCID: 9490534

Digital health interventions for musculoskeletal pain conditions: A systematic review and meta-analysis of Randomized Controlled Trials

  • Pim Peter Valentijn; 
  • Liza Tymchenko; 
  • Teddy Jacobson; 
  • Jakob Kroman; 
  • Claus W. Biermann; 
  • Mohamed Atef AlMoslemany; 
  • Rosa Ymkje Arends

ABSTRACT

Background:

Digital health solutions can provide musculoskeletal populations with high-reach, low-cost, easily accessible, and scalable patient education and self-management interventions that meet time and resource restrictions.

Objective:

The main objective is to determine the effectiveness of digital health interventions for people with musculoskeletal pain conditions (i.e. low back pain, neck pain, shoulder pain, knee pain, elbow pain, ankle pain and whiplash).

Methods:

We searched the PubMed National Library of Medicine database (from 1974 to August 2021), and selected randomized, controlled trials of digital health interventions in the target population of musculoskeletal pain patients with a minimum follow-up of 1 month. Two researchers independently screened and extracted the data.

Results:

A total of 56 eligible studies were included covering 9359 participants, with a mean follow-up of 25 weeks. In moderate quality evidence, digital health interventions had a small effect on pain (standardized mean difference (SMD), 0.19; 95% confidence interval [95% CI], 0.06 to 0.32), disability (SMD, 0.14; 95% CI, 0.03 to 0.25), quality of life (SMD, 0.22; 95% CI, 0.07 to 0.36), emotional functioning (SMD, 0.24; 95% CI, 0.12 to 0.35) and self-management (SMD, 0.14; 95% CI, 0.05 to 0.24).

Conclusions:

Moderate quality-evidence supports the conclusion that digital health interventions are effective to reduce pain and improve functioning and self-management in musculoskeletal pain conditions. Low quality evidence indicated that digital health can improve quality of life and global treatment improvement. There are few research on the influence of digital health on expenses, knowledge, overall improvement, range of motion, muscle strength, and fidelity of implementation.


 Citation

Please cite as:

Valentijn PP, Tymchenko L, Jacobson T, Kroman J, Biermann CW, AlMoslemany MA, Arends RY

Digital Health Interventions for Musculoskeletal Pain Conditions: Systematic Review and Meta-analysis of Randomized Controlled Trials

J Med Internet Res 2022;24(9):e37869

DOI: 10.2196/37869

PMID: 36066943

PMCID: 9490534

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