Maintenance Notice

Due to necessary scheduled maintenance, the JMIR Publications website will be unavailable from Wednesday, July 01, 2020 at 8:00 PM to 10:00 PM EST. We apologize in advance for any inconvenience this may cause you.

Who will be affected?

Accepted for/Published in: JMIR Medical Informatics

Date Submitted: Mar 8, 2022
Date Accepted: Apr 19, 2022

The final, peer-reviewed published version of this preprint can be found here:

Conditional Probability Joint Extraction of Nested Biomedical Events: Design of a Unified Extraction Framework Based on Neural Networks

Wang Y, Wang J, Lin H, Lu H, Xu B, Zhang Y

Conditional Probability Joint Extraction of Nested Biomedical Events: Design of a Unified Extraction Framework Based on Neural Networks

JMIR Med Inform 2022;10(6):e37804

DOI: 10.2196/37804

PMID: 35671070

PMCID: 9214613

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Conditional Probability Joint Extraction of Nested Biomedical Events: Design of a Unified Extraction Framework Based on Neural Networks

  • Yan Wang; 
  • Jian Wang; 
  • Hongfei Lin; 
  • Huiyi Lu; 
  • Bing Xu; 
  • Yijia Zhang

ABSTRACT

Background:

Extracting events is essential in natural language processing. In the biomedical field, the nested event phenomenon (event A is a participating role of event B) makes extracting this event more difficult than extracting a single event. Therefore, the performance of nested biomedical events is always underwhelming. In addition, previous works rely on a pipeline to build an event extraction model, which ignores the dependence between trigger recognition and event argument detection tasks and produces significant cascading errors.

Objective:

We aim to design a unified framework to train biomedical event triggers and arguments jointly, and improve the performance of extracting nested biomedical events.

Methods:

We proposed an end-to-end joint extraction model that considers the probability distribution of triggers to alleviate the cascading errors. Moreover, we integrate the syntactic structure into an attention-based gate GCN to capture potential interrelations between triggers and related entities, which improves the performance of extracting nested biomedical events.

Results:

The experimental results demonstrate that our proposed method achieves the best F1-score on the MLEE biomedical event extraction corpus and achieves a favorable performance on the BioNLP-ST 2011 GE corpus.

Conclusions:

Our CPJE model is good at extracting nested biomedical events because of the joint extraction mechanism and the syntax graph structure. Moreover, because our model does not rely on external knowledge and specific feature engineering, it has a particular generalization performance.


 Citation

Please cite as:

Wang Y, Wang J, Lin H, Lu H, Xu B, Zhang Y

Conditional Probability Joint Extraction of Nested Biomedical Events: Design of a Unified Extraction Framework Based on Neural Networks

JMIR Med Inform 2022;10(6):e37804

DOI: 10.2196/37804

PMID: 35671070

PMCID: 9214613

Download PDF


Request queued. Please wait while the file is being generated. It may take some time.

© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.