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Accepted for/Published in: JMIR Research Protocols

Date Submitted: Feb 6, 2022
Date Accepted: May 17, 2022

The final, peer-reviewed published version of this preprint can be found here:

The First National Remote Emergency System for Malignant Hyperthermia (MH-NRES) in China: Protocol for the Design, Development, and Evaluation of a WeChat Applet

Yu H, Tan L, Teng Y, Xu Z, Xiao K, Yin J, Zuo Y, Zhu T, Deng X

The First National Remote Emergency System for Malignant Hyperthermia (MH-NRES) in China: Protocol for the Design, Development, and Evaluation of a WeChat Applet

JMIR Res Protoc 2022;11(6):e37084

DOI: 10.2196/37084

PMID: 35687418

PMCID: 9233253

First National Remote Emergency System for Malignant Hyperthermia (MH-NRES) in China: Protocol for a WeChat applet Design, Development, and Evaluation

  • Hong Yu; 
  • Lingcan Tan; 
  • Yi Teng; 
  • Zhao Xu; 
  • Kun Xiao; 
  • Jin Yin; 
  • Yunxia Zuo; 
  • Tao Zhu; 
  • Xiaoqian Deng

ABSTRACT

Background:

Malignant hyperthermia (MH) is a rare life-threatening anesthetic emergency. With respect to the high fatality rate, difficulty in early recognition and the lack of disease-specific drug (i.e., dantrolene) in China, more effort is need to strengthen early diagnosis and effective treatment of MH emergency. Nowadays, mobile health applications (mHealth apps) are changing the way of medical practice, which are an accessible tool for helping anesthesiologists to deal with MH crisis. However, no related mHealth-based emergency system is available now.

Objective:

The aim of this study is to outline the methods for a WeChat applet development used to design National Remote Emergency System for Malignant Hyperthermia (MH-NRES) in China, as well as the methods for evaluation of the user experience and perception of the system.

Methods:

The system adopts client-server architecture, with a custom user interface operating as clients and the back-end system operating as the server. The client-side software was developed using uni-app technology with Vue.js-based framework, which consists of six modules: quick diagnosis, dantrolene mobilization, instruction on dantrolene use, MH treatment, recovery period treatment, and DNA test and Biopsy. The back-end system was developed based on the Spring framework. The system will be evaluated by administrating a modified user version of the Mobile App Rating Scale (uMARS). The pilot testing in Sichuan Province of China and the following evaluation on a national scale are planned.

Results:

The theoretical framework design of this system took a total of 4 months (May-August 2021). The development of the system is planned to take 4 months (September-December 2021). The pilot testing in Sichuan Province is planned to take 2 months and the following evaluation to take 6 months.

Conclusions:

We have described a novel approach using the WeChat applet to develop the MH-NRES which can help anesthesiologists in China with rapid diagnosis, effectively management and dantrolene mobilization in real time when MH cases occur and can provide subsequently gene diagnostic services and family counselling. Findings from the evaluation process is expected to suggest that this system is both feasible and welcomed by anesthesiologists. Clinical Trial: None


 Citation

Please cite as:

Yu H, Tan L, Teng Y, Xu Z, Xiao K, Yin J, Zuo Y, Zhu T, Deng X

The First National Remote Emergency System for Malignant Hyperthermia (MH-NRES) in China: Protocol for the Design, Development, and Evaluation of a WeChat Applet

JMIR Res Protoc 2022;11(6):e37084

DOI: 10.2196/37084

PMID: 35687418

PMCID: 9233253

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