Accepted for/Published in: JMIR Research Protocols
Date Submitted: Nov 10, 2021
Open Peer Review Period: Nov 10, 2021 - Jan 5, 2022
Date Accepted: Feb 26, 2022
(closed for review but you can still tweet)
Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.
The Brain and Early Experience Study: Protocol for a Prospective Observational Study
ABSTRACT
Background:
Children raised in conditions of poverty (or near-poverty) are at risk for nonoptimal mental health, educational, and occupational outcomes, many of which may be precipitated by individual differences in EF skills that first emerge in early childhood.
Objective:
The Brain and Early Experience (BEE) study considers prenatal and postnatal experiences that may mediate the association between poverty and EF skills, including their neural substrates. This manuscript describes (1) the study rationale and aims; (2) research design issues, including sample size determination, the recruitment strategy, and participant characteristics; and (3) a summary of developmental assessment points, procedures, and measures used to test the study hypotheses.
Methods:
This is a prospective longitudinal study examining multiple pathways by which poverty influences normative variations in executive function (EF) skills in early childhood. It is funded by the National Institute of Child Health and Human Development with Institutional Review Board approval. Recruitment is completed with a sample of N = 203 and data collection is expected to continue from September of 2018 to February 2024.
Results:
Analysis plans and validation data supporting the recruitment strategy is provided.
Conclusions:
BEE Study data and analyses will help elucidate the complex interplay between prenatal and postnatal risk factors that may undermine critical neurocognitive developmental outcomes in early childhood.
Conclusions:
Findings will help elucidate the complex interplay between prenatal and postnatal risk factors affecting critical neurocognitive developmental outcomes in early childhood.
Citation
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Copyright
© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.