Maintenance Notice

Due to necessary scheduled maintenance, the JMIR Publications website will be unavailable from Wednesday, July 01, 2020 at 8:00 PM to 10:00 PM EST. We apologize in advance for any inconvenience this may cause you.

Who will be affected?

Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Oct 22, 2021
Open Peer Review Period: Oct 22, 2021 - Nov 1, 2021
Date Accepted: Nov 30, 2021
Date Submitted to PubMed: Jan 4, 2022
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

A Deep Residual U-Net Algorithm for Automatic Detection and Quantification of Ascites on Abdominopelvic Computed Tomography Images Acquired in the Emergency Department: Model Development and Validation

Ko H, Huh J, Kim KW, Chung H, Ko Y, Kim JK, Lee JH, Lee J

A Deep Residual U-Net Algorithm for Automatic Detection and Quantification of Ascites on Abdominopelvic Computed Tomography Images Acquired in the Emergency Department: Model Development and Validation

J Med Internet Res 2022;24(1):e34415

DOI: 10.2196/34415

PMID: 34982041

PMCID: 8764611

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

A deep Residual U-Net algorithm for automatic detection and quantification of ascites on the abdominopelvic computed tomography acquired in the emergency department

  • Hoon Ko; 
  • Jimi Huh; 
  • Kyung Won Kim; 
  • Heewon Chung; 
  • Yousun Ko; 
  • Jai Keun Kim; 
  • Jei Hee Lee; 
  • Jinseok Lee

ABSTRACT

Background:

Detection and quantification of intraabdominal free fluid (i.e., ascites) on computed tomography (CT) are essential processes to find emergent or urgent conditions in patients. In an emergent department, automatic detection and quantification of ascites will be beneficial.

Objective:

We aimed to develop an artificial intelligence (AI) algorithm for the automatic detection and quantification of ascites simultaneously using a single deep learning model (DLM).

Methods:

2D deep learning models (DLMs) based on a deep residual U-Net, U-Net, bi-directional U-Net, and recurrent residual U-net were developed to segment areas of ascites on an abdominopelvic CT. Based on segmentation results, the DLMs detected ascites by classifying CT images into ascites images and non-ascites images. The AI algorithms were trained using 6,337 CT images from 160 subjects (80 with ascites and 80 without ascites) and tested using 1,635 CT images from 40 subjects (20 with ascites and 20 without ascites). The performance of AI algorithms was evaluated for diagnostic accuracy of ascites detection and for segmentation accuracy of ascites areas. Of these DLMs, we proposed an AI algorithm with the best performance.

Results:

The segmentation accuracy was the highest in the deep residual U-Net with a mean intersection over union (mIoU) value of 0.87, followed by U-Net, bi-directional U-Net, and recurrent residual U-net (mIoU values 0.80, 0.77, and 0.67, respectively). The detection accuracy was the highest in the deep residual U-net (0.96), followed by U-Net, bi-directional U-net, and recurrent residual U-net (0.90, 0.88, and 0.82, respectively). The deep residual U-net also achieved high sensitivity (0.96) and high specificity (0.96).

Conclusions:

We propose the deep residual U-net-based AI algorithm for automatic detection and quantification of ascites on abdominopelvic CT scans, which provides excellent performance.


 Citation

Please cite as:

Ko H, Huh J, Kim KW, Chung H, Ko Y, Kim JK, Lee JH, Lee J

A Deep Residual U-Net Algorithm for Automatic Detection and Quantification of Ascites on Abdominopelvic Computed Tomography Images Acquired in the Emergency Department: Model Development and Validation

J Med Internet Res 2022;24(1):e34415

DOI: 10.2196/34415

PMID: 34982041

PMCID: 8764611

Download PDF


Request queued. Please wait while the file is being generated. It may take some time.

© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.