Accepted for/Published in: JMIR Public Health and Surveillance
Date Submitted: Apr 25, 2021
Open Peer Review Period: Apr 25, 2021 - Jun 20, 2021
Date Accepted: Feb 21, 2022
(closed for review but you can still tweet)
Health-related Quality of Life of HIV-positive and HIV-negative Pregnant Women in Impoverished area: A Cross-sectional Study
ABSTRACT
Background:
Liangshan prefecture of Sichuan province is an impoverished mountainous area in China, where the annual number of HIV-positive pregnant women accounts for about 10% of China's total in recent decades. In general, pregnant women living in impoverished mountainous may be different with the others on the physical and mental health.
Objective:
This study aims to study the health-related quality of life (HRQoL) of pregnant women living with HIV in impoverished area.
Methods:
From December 2018 to January 2019, HIV-positive and HIV-negative pregnant women were recruited in Liangshan Prefecture, Sichuan Province. Questionnaires were designed to collect their demographic data, while the EQ-5D was used to measure the HRQoL of their when they were in the second trimester of pregnancy -- months 4, 5, and 6, and their quantitative health scores which were converted into corresponding utility values using the Chinese Utility Value Integral System (TTO coefficient).
Results:
A total of 250 pregnant women (HIV-positive, n=133; HIV-negative, n=117) were enrolled in the study. Among them, 55 (41.35%) and 75 (64.10%) of HIV-positive and HIV-negative pregnant women respectively were in perfect health. The median health utility value of the 250 pregnant women was 0.961 (-0.046~0.961), and those of the HIV-positive and HIV-negative pregnant women were 0.875 (0.424~0.961) and 0.961 (-0.046~0.961) respectively. Statistical differences was only found in the dimension of anxiety/depression between the two groups (P=0.002), and no significant difference in the distribution of health utility indices between the two groups in the aspects of maternal age, degree of education, occupation, family income, prenatal examination count, family size, and medical insurance category was found.
Conclusions:
Most pregnant women experience satisfactory HRQoL in impoverished mountainous area. HIV-negative pregnant women had an edge over HIV-positive pregnant women, and there were significant differences in anxiety/depression dimensions between the two groups.
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