JMIR Publications

ABSTRACT

Background:

Mind-body interventions have the potential to positively impact the symptom burden associated with primary biliary cholangitis (PBC). Interventions are more likely to be effective if they are informed by a theoretical framework. The Behaviour Change Wheel (BCW) and the behaviour change technique taxonomy version 1 (BCTv1) provide frameworks for intervention development.

Objective:

This paper describes how theory has guided the development of a 12-week multicomponent mind-body wellness intervention for PBC.

Methods:

The steps of the BCW intervention development were followed including specifying the target behaviour; explaining barriers and facilitators using the Capability, Opportunity, Motivation, Behaviour and Theoretical Domains Frameworks; identifying intervention functions to target explanatory domains; and selecting relevant behaviour change techniques to address intervention functions. Qualitative data from patients with inflammatory bowel disease using an earlier version of the program, and feedback from a PBC patient advisory team, were used to guide intervention development.

Results:

Barriers and facilitators to intervention participation associated with capability, opportunity, and motivation were identified. Intervention functions, and behaviour change techniques were identified to target each barrier and facilitator.

Conclusions:

The Peace Power PackPBC intervention was developed to help individuals with PBC manage their symptom burden. The theoretical frameworks employed in this intervention provide direction on targeting antecedents of behaviour, and allow standardised reporting of intervention components. Clinical Trial: ClinicalTrials.gov NCT04791527