Previously submitted to: JMIR Bioinformatics and Biotechnology (no longer under consideration since Feb 23, 2021)
Date Submitted: Feb 13, 2021
Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.
Automatic detection of the Cyclic Alternating Pattern of sleep and diagnosis of sleep-related pathologies
ABSTRACT
The Cyclic Alternating Pattern is a periodic electroencephalogram activity occurring during No Rapid Eye Movement sleep. It is a marker of sleep instability and correlated with several sleep-related pathologies. In this article, considering the connection between heart and brain of people, by statistically analysising and comparing the cardiopulmonary characteristics of people with no pathology and patients with sleep-related diseases, an automatic recognition scheme of Cyclic Alternating Pattern is proposed based on the Cardiopulmonary Resonance Indices. Using improved Hidden Markov and Random Forest, the scheme combines both the measurements of coupling state and the stability of the cardiopulmonary system during sleep. The average recognition rate of A-phase reaches 84.67% and F1 score reaches 80.35%. Results show that our scheme could automatically recognize the Cyclic Alternating Pattern accurately, and diagnose insomnia and narcolepsy.
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