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Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Jan 26, 2021
Open Peer Review Period: Jan 26, 2021 - Mar 23, 2021
Date Accepted: Apr 3, 2021
Date Submitted to PubMed: Apr 27, 2021
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Deep Convolutional Neural Network–Based Computer-Aided Detection System for COVID-19 Using Multiple Lung Scans: Design and Implementation Study

Ghaderzadeh M, Asadi F, Jafari R, Bashash D, Abolghasemi H, Aria M

Deep Convolutional Neural Network–Based Computer-Aided Detection System for COVID-19 Using Multiple Lung Scans: Design and Implementation Study

J Med Internet Res 2021;23(4):e27468

DOI: 10.2196/27468

PMID: 33848973

PMCID: 8078376

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Deep CNN-Based CAD System for COVID-19 Detection Using Multiple Lung CT Scans

  • Mustafa Ghaderzadeh; 
  • Farkhondeh Asadi; 
  • Ramezan Jafari; 
  • Davood Bashash; 
  • Hassan Abolghasemi; 
  • Mehrad Aria

ABSTRACT

Background:

Due to the COVID-19 pandemic and the imminent collapse of healthcare systems following the excessive consumption of financial, hospital, and medicinal resources, the World Health Organization (WHO) changed the alert level on the COVID-19 pandemic from high to very high. Meanwhile, the world began to favor less expensive and more precise COVID-19 detection methods. Machine vision-based COVID-19 detection methods especially Deep learning as a diagnostic technique in the early stages of the disease have found great importance during the pandemic.

Objective:

This study aimed to design a highly efficient Computer-Aided Detection (CAD) system for COVID-19 by using a NASNet-based algorithm. n images of 190 persons suspected of COVID-19, was used.

Methods:

A state-of-the-art pre-trained CNN network for image feature extraction, called NASNet, was adopted to identify patients with COVID-19 in the first stages of the disease. A local dataset, comprising 10153 CT scan images of 190 persons suspected of COVID-19, was used.

Results:

After fitting on the training dataset, hyper-parameter tuning and finally topological alterations of the classifier block, the proposed NASNet-based model was evaluated on the test dataset and yielded remarkable results. The proposed model's performance achieved a detection sensitivity, specificity, and accuracy of 0.999, 0.986, and 0.996, respectively.

Conclusions:

The proposed model achieved acceptable results in the categorization of two data classes. Therefore, a CAD system was designed based on this model for COVID-19 detection using multiple lung CT scans. The system managed to differentiate all the COVID-19 cases from non-COVID-19 ones without any error in the application phase. Overall, the proposed deep learning-based CAD system can greatly aid radiologists in the detection of COVID-19 in its early stages. During the COVID-19 pandemic, the use of CAD system as a screening tool accelerates the process of disease detection and prevents the loss of healthcare resources.


 Citation

Please cite as:

Ghaderzadeh M, Asadi F, Jafari R, Bashash D, Abolghasemi H, Aria M

Deep Convolutional Neural Network–Based Computer-Aided Detection System for COVID-19 Using Multiple Lung Scans: Design and Implementation Study

J Med Internet Res 2021;23(4):e27468

DOI: 10.2196/27468

PMID: 33848973

PMCID: 8078376

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