Accepted for/Published in: JMIR Research Protocols
Date Submitted: Jan 13, 2021
Date Accepted: May 10, 2021
Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.
Web-based multifaceted approach in community-based screening in HIV self-testing: protocol for randomized community trial among female sex workers in Indonesia
ABSTRACT
Background:
The HIV epidemic in Indonesia continues to be concentrated among key populations including female sex workers (FSW). However, increasing HIV testing among this sub-population continues to be a challenge, necessitating exploration into alternatives testing modalities.
Objective:
The objective of this study was to test whether the addition of oral fluid test as an alternative testing modality will increase the number of FSW who receive HIV testing.
Methods:
We undertook a community-randomized trial in 23 national priority districts with existing package of HIV community outreach services. The trial consisted of 15 intervention districts and 8 control districts. In the control districts, implementing units of HIV program administered the standard of care while in the intervention districts, an additional HIV self-testing option using oral fluid test was given as a community-based screening. Participants with reactive screening results will be encouraged to undergo HIV testing at a health facility to confirm their diagnosis and subsequent antiretroviral treatment. Multiple means of recruitment were deployed including through outreach workers and social media campaign. Due in large part to the COVID-19 pandemic, most research activities were conducted online.
Results:
17,962 FSWs were reached in the intervention sites, 45.5% (n=8,176/17,962) accepted testing, 18.9% of whom accepted OFT (n= 1,545/8,176). A total of 1.3% (n=106/8,176) participants were confirmed HIV positive. In the control districts, 7,653 FSWs were reached, 45.4% (n=3,471/7.653) received testing, 0.8% (n=29/3,471) were confirmed HIV positive. Post-test surveys for participants receiving OFT indicated overall high satisfaction and intention to use. Through the social media campaign, there were also people who registered independently for OFT but did not identify as FSW. They were eventually not eligible to participate but their interest point to the possibility of implementing HIV self-testing to general population.
Conclusions:
The addition of HIV self-testing to standard of care supported by a web-based data collection system was able to result in higher HIV testing and higher case finding among female sex workers in Indonesia. High satisfaction of OFT users and the interest of general population towards this alternative testing modality are promising for scaling up this strategy nationally. Clinical Trial: ClinicalTrials.gov, number NCT04578145
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