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Yamada R, Isaji S, Fujii T, Mizuno S, Kishiwada M, Murata Y, Hayasaki A, Inoue H, Umeda Y, Tanaka K, Hamada Y, Tsuboi J, Kato T, Kondo Y, Matsuda S, Watanabe N, Ogura T, Tamaru S
Improving the Prognosis of Pancreatic Cancer Through Early Detection: Protocol for a Prospective Observational Study
Improving prognosis in pancreatic cancer through early detection: a prospective observational study
Reiko Yamada;
Shuji Isaji;
Takehiro Fujii;
Shugo Mizuno;
Masashi Kishiwada;
Yasuhiro Murata;
Aoi Hayasaki;
Hiroyuki Inoue;
Yuhei Umeda;
Kyosuke Tanaka;
Yasuhiko Hamada;
Junya Tsuboi;
Toshio Kato;
Yoshihiro Kondo;
Shinsuke Matsuda;
Noriko Watanabe;
Toru Ogura;
Satoshi Tamaru
ABSTRACT
Background:
Pancreatic cancer is associated with high mortality and rates of detection are very low, meaning that the disease is typically diagnosed at an advanced stage. A number of risk factors for pancreatic cancer have been reported and may be used to identify individuals at high risk for the development of this disease.
Objective:
The aim of this trial is to evaluate a scoring metric for systematic early detection of pancreatic cancer in Mie Prefecture, Japan.
Methods:
Eligible patients aged 18 years and older will be referred from participating clinics in the Tsu city area to Mie University Graduate School, Faculty of Medicine, Gastroenterology and Hepatology until September 30, 2022. Participants will undergo a detailed examination for pancreatic cancer. Data collection will include diagnostic and follow-up imaging data and disease staging information.
Results:
The study was initiated in September 2020 and aims to recruit at least 150 patients in a 2-year period. Final data analysis is expected to be complete by March, 2025.
Conclusions:
This prospective, observational study will provide insights into the feasibility of using a scoring system for the early detection of pancreatic cancer, thus potentially improving the survival outcomes of patients diagnosed with this serious disease. Clinical Trial: UMIN000041624
Citation
Please cite as:
Yamada R, Isaji S, Fujii T, Mizuno S, Kishiwada M, Murata Y, Hayasaki A, Inoue H, Umeda Y, Tanaka K, Hamada Y, Tsuboi J, Kato T, Kondo Y, Matsuda S, Watanabe N, Ogura T, Tamaru S
Improving the Prognosis of Pancreatic Cancer Through Early Detection: Protocol for a Prospective Observational Study