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Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Sep 16, 2020
Date Accepted: Feb 16, 2021

The final, peer-reviewed published version of this preprint can be found here:

Immersive Virtual Reality and Ocular Tracking for Brain Mapping During Awake Surgery: Prospective Evaluation Study

Casanova M, Clavreul A, Soulard G, Delion M, Aubin G, Ter Minassian A, Seguier R, Menei P

Immersive Virtual Reality and Ocular Tracking for Brain Mapping During Awake Surgery: Prospective Evaluation Study

J Med Internet Res 2021;23(3):e24373

DOI: 10.2196/24373

PMID: 33759794

PMCID: 8074984

Immersive virtual reality and ocular tracking for brain mapping during awake surgery

  • Morgane Casanova; 
  • Anne Clavreul; 
  • Gwénaëlle Soulard; 
  • Matthieu Delion; 
  • Ghislaine Aubin; 
  • Aram Ter Minassian; 
  • Renaud Seguier; 
  • Philippe Menei

ABSTRACT

Background:

Language mapping during awake brain surgery is now a standard procedure. However, mapping is more rarely performed for other cognitive functions important for social interaction, such as visuo-spatial cognition and non-verbal language, including facial expressions and eye gaze. The main reason for this is the lack of tasks fully compatible with the restrictive environment of an operating room and awake brain surgery procedures.

Objective:

To evaluate the feasibility and safety of a virtual reality headset (VRH) with eye tracking and an immersive visuo-spatial and social VR experience in patients undergoing awake craniotomy.

Methods:

Fifteen patients with brain tumours near the language area were included. Language mapping was performed with a naming task, DO 80, presented on a digital tablet and then in two and three dimensions via the VRH. The patients were also immersed in a visuo-spatial and social VR experience.

Results:

None of the patients experienced VR sickness. Two patients suffered an intraoperative focal seizure without consequence, but there was no reason to attribute this to VRH use. Patients were able to perform VR tasks. Eye tracking was functional, enabling the medical team to analyse the patients’ attention and exploration of the visual field of the VRH directly.

Conclusions:

We showed that it is possible and safe, during awake brain surgery, to immerse the patient in an interactive virtual environment, paving the way for new VR-based brain mapping procedures. Clinical Trial: ClinicalTrials.gov NCT03010943


 Citation

Please cite as:

Casanova M, Clavreul A, Soulard G, Delion M, Aubin G, Ter Minassian A, Seguier R, Menei P

Immersive Virtual Reality and Ocular Tracking for Brain Mapping During Awake Surgery: Prospective Evaluation Study

J Med Internet Res 2021;23(3):e24373

DOI: 10.2196/24373

PMID: 33759794

PMCID: 8074984

Per the author's request the PDF is not available.

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