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Accepted for/Published in: JMIR Public Health and Surveillance

Date Submitted: Sep 4, 2020
Date Accepted: Dec 14, 2020
Date Submitted to PubMed: Dec 14, 2020

The final, peer-reviewed published version of this preprint can be found here:

Improving Detection of Disease Re-emergence Using a Web-Based Tool (RED Alert): Design and Case Analysis Study

Parikh NK, Daughton AR, Rosenberger WE, Aberle DJ, Chitanvis ME, Altherr FM, Velappan N, Fairchild G, Deshpande A

Improving Detection of Disease Re-emergence Using a Web-Based Tool (RED Alert): Design and Case Analysis Study

JMIR Public Health Surveill 2021;7(1):e24132

DOI: 10.2196/24132

PMID: 33316766

PMCID: 7819778

Combining Data, Machine Learning, and Visual Analytics to Improve Detection of Disease Re-emergence: The Re-emerging Disease Alert Tool

  • Nidhi Kiranbhai Parikh; 
  • Ashlynn Rae Daughton; 
  • William Earl Rosenberger; 
  • Derek Jacob Aberle; 
  • Maneesha Elizabeth Chitanvis; 
  • Forest Michael Altherr; 
  • Nileena Velappan; 
  • Geoffrey Fairchild; 
  • Alina Deshpande

ABSTRACT

Background:

Currently, the identification of infectious disease re-emergence is performed without describing specific quantitative criteria that can be used to identify re-emergence events consistently. This practice may lead to irreproducible assessments of high-consequence, public-health events and in turn poor disease response prioritization, misallocation of resources, and ineffective mitigation. In addition, identification of factors contributing to local disease re-emergence and assessment of global disease re-emergence require access to data about a large number of factors at the local level and disease case counts for the entire world. Collection and systematic analysis of this data may be time consuming.

Objective:

This paper presents Re-emerging Disease Alert (RED Alert), a web-based tool designed to help public health officials detect and understand infectious disease re-emergence. It uses machine learning and visual analytics to help detect potential local disease re-emergence, identify potential factors contributing the local re-emergence, and assess potential for the global disease re-emergence.

Methods:

RED Alert collects and stores various disease-related data (e.g., case counts, vaccination rates, and related indicators) and provides machine learning and visual analytics to help detect and understand disease re-emergence through both local and global contextual data analysis.

Results:

RED Alert is a web-based, easy to use, and freely available (at https://redalert.bsvgateway.org/) tool that can help detect and understand disease re-emergence for following diseases at the country level and yearly time scale: measles, cholera, dengue, and yellow fever. We present a few case studies to show utility of the tool.

Conclusions:

To the best of our knowledge, this is the first tool that focuses specifically on disease re-emergence and addresses the important challenges mentioned above.


 Citation

Please cite as:

Parikh NK, Daughton AR, Rosenberger WE, Aberle DJ, Chitanvis ME, Altherr FM, Velappan N, Fairchild G, Deshpande A

Improving Detection of Disease Re-emergence Using a Web-Based Tool (RED Alert): Design and Case Analysis Study

JMIR Public Health Surveill 2021;7(1):e24132

DOI: 10.2196/24132

PMID: 33316766

PMCID: 7819778

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