Maintenance Notice

Due to necessary scheduled maintenance, the JMIR Publications website will be unavailable from Wednesday, July 01, 2020 at 8:00 PM to 10:00 PM EST. We apologize in advance for any inconvenience this may cause you.

Who will be affected?

Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Sep 2, 2020
Date Accepted: Apr 4, 2021

The final, peer-reviewed published version of this preprint can be found here:

Patient Recruitment Into a Multicenter Clinical Cohort Linking Electronic Health Records From 5 Health Systems: Cross-sectional Analysis

Bennett W, Bramante C, Rothenberger S, Kraschnewski J, Herring S, Lent M, Clark J, Conroy M, Lehmann H, Cappella N, Gauvey-Kern M, McCullough J, McTigue K

Patient Recruitment Into a Multicenter Clinical Cohort Linking Electronic Health Records From 5 Health Systems: Cross-sectional Analysis

J Med Internet Res 2021;23(5):e24003

DOI: 10.2196/24003

PMID: 34042604

PMCID: 8193474

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Enrollment into a multi-center clinical cohort linking electronic health records from five health systems: The PaTH Clinical Research Network

  • Wendy Bennett; 
  • Carolyn Bramante; 
  • Scott Rothenberger; 
  • Jennifer Kraschnewski; 
  • Sharon Herring; 
  • Michelle Lent; 
  • Jeanne Clark; 
  • Molly Conroy; 
  • Harold Lehmann; 
  • Nickie Cappella; 
  • Megan Gauvey-Kern; 
  • Jody McCullough; 
  • Kathleen McTigue

ABSTRACT

Background:

There is growing interest in identifying and recruiting research participants from health systems using electronic health records (EHRs). However, few studies have described the practical aspects of recruiting or compared electronic recruitment methods to in person recruitment, particularly across health systems.

Objective:

To describe the process and efficiency of the recruitment process and participant characteristics by strategy.

Methods:

EHR-based eligibility criteria included being an adult patient engaged in outpatient primary or bariatric surgery care at one of 5 health systems in the PaTH Clinical Research Network with >= 2 weights and one height in the EHR in the last 5 years. Recruitment strategies varied by site and included one or more of the following: in person recruitment by study staff from primary care and bariatric surgery outpatient sites, U.S. postal mail recruitment letters, secure e-mail and direct EHR recruitment through secure patient web portals. We used descriptive statistics to evaluate participant characteristics and recruitment efficiency by modality.

Results:

Total number of eligible patients for study participation from 5 health systems was 5,051,187. Of these, 40,048 (0.8%) were invited to enter an EHR-based cohort study and 1,085 were enrolled. Recruitment efficiency was highest for in person recruitment (33%), followed by electronic messaging (2.9%), including e-mail (2.9%) and EHR patient portal messages (2.9%). Overall, 779 (65.7%) were enrolled through electronic messaging, which also had greater rates of recruitment of Black patients compared with the other modalities.

Conclusions:

We recruited a total of 1,085 primary care and bariatric surgery patients using four recruitment modalities. The recruitment efficiency was 2.9% for email and patient portal, with the majority of participants recruited electronically. This study can inform the design of research studies using EHR-based recruitment. Clinical Trial: NA


 Citation

Please cite as:

Bennett W, Bramante C, Rothenberger S, Kraschnewski J, Herring S, Lent M, Clark J, Conroy M, Lehmann H, Cappella N, Gauvey-Kern M, McCullough J, McTigue K

Patient Recruitment Into a Multicenter Clinical Cohort Linking Electronic Health Records From 5 Health Systems: Cross-sectional Analysis

J Med Internet Res 2021;23(5):e24003

DOI: 10.2196/24003

PMID: 34042604

PMCID: 8193474

Download PDF


Request queued. Please wait while the file is being generated. It may take some time.

© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.