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Accepted for/Published in: JMIR Formative Research

Date Submitted: Aug 12, 2020
Date Accepted: Oct 15, 2021
Date Submitted to PubMed: Dec 3, 2021

The final, peer-reviewed published version of this preprint can be found here:

Predicting Risk of Stroke From Lab Tests Using Machine Learning Algorithms: Development and Evaluation of Prediction Models

Alanazi E, Abdou A, Luo J

Predicting Risk of Stroke From Lab Tests Using Machine Learning Algorithms: Development and Evaluation of Prediction Models

JMIR Form Res 2021;5(12):e23440

DOI: 10.2196/23440

PMID: 34860663

PMCID: 8686476

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Predicting risk of stroke from lab tests using machine learning algorithms

  • Eman Alanazi; 
  • Alaa Abdou; 
  • Jake Luo

ABSTRACT

Stroke, a cerebrovascular disease, is one of the major causes of death. It is also causing a health burden for both the patients and the healthcare systems. One of the important risk factors of stroke is health behavior which is an increasing focus of prevention. In addition, chronic diseases such as hypertension, diabetes, cardiac diseases, and asthma are potential risk factors for stroke. There are a lot of machine learning that built using predictors such as lifestyle or radiology imaging. However, there are no models built using lab tests. The aim of the study is to fill this gap by building prediction models to predict stroke from lab tests. We utilized the National Health and Nutrition Examination Survey (NHNES) data sets to develop models that would predict stroke from patient lab tests. We found that accurate and sensitive machine learning models can be created to predict stroke from lab tests. The results showed that prediction with the best tested algorithm random forest could reach the highest accuracy (ACC = 0.96) when all the attributes were used. The model proposed can be integrated with electronic health records to provide a real-time prediction of stroke from lab tests. Due to the data, we could not predict the type of stroke wither hemorrigic or ischemic. In future studies, we aim to use data that provide different types of stroke and explore the data to build a prediction model of each type.


 Citation

Please cite as:

Alanazi E, Abdou A, Luo J

Predicting Risk of Stroke From Lab Tests Using Machine Learning Algorithms: Development and Evaluation of Prediction Models

JMIR Form Res 2021;5(12):e23440

DOI: 10.2196/23440

PMID: 34860663

PMCID: 8686476

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