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Accepted for/Published in: JMIR Medical Informatics

Date Submitted: Aug 12, 2020
Date Accepted: Dec 12, 2020

The final, peer-reviewed published version of this preprint can be found here:

A Novel Convolutional Neural Network for the Diagnosis and Classification of Rosacea: Usability Study

Zhao Z, Wu C, Zhang S, He F, Liu F, Wang B, Huang Y, Shi W, Jian D, Xie H, Yeh CY, Li J

A Novel Convolutional Neural Network for the Diagnosis and Classification of Rosacea: Usability Study

JMIR Med Inform 2021;9(3):e23415

DOI: 10.2196/23415

PMID: 33720027

PMCID: 8077711

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Applying Artificial Intelligence for the Diagnosis and Classification of Rosacea

  • Zhixiang Zhao; 
  • CheMing Wu; 
  • Shuping Zhang; 
  • Fanping He; 
  • Fangfen Liu; 
  • Ben Wang; 
  • Yingxue Huang; 
  • Wei Shi; 
  • Dan Jian; 
  • Hongfu Xie; 
  • Chao-Yuan Yeh; 
  • Ji Li

ABSTRACT

Background:

Rosacea is a chronic inflammatory disease with variable clinical presentations including transient flushing, fixed erythema, papules, pustules and phymatous changes on the central face. Owing to the diversity of clinical manifestations, the lack of objective biochemical examinations and non-specificity of histopathology, accurate identification of rosacea is a big challenge. Artificial intelligence has emerged as a potential tool in the identification and evaluation of some skin diseases such as melanoma, basal cell carcinoma and psoriasis.

Objective:

In this work, we utilized convolution neural networks (CNN) to identify the clinical photos (from three different angles) of patients with rosacea and other diseases that would be easily confused with rosacea (such as acne, seborrheic dermatitis and eczema).

Methods:

In this work, we utilized convolution neural networks (CNN) to identify the clinical photos (from three different angles) of patients with rosacea and other diseases that would be easily confused with rosacea (such as acne, seborrheic dermatitis and eczema).

Results:

The CNN in our study achieved an overall accuracy and precision of 0.914 and 0.898, with an area under the receiver operating characteristic curve (AUROC) of 0.972 for the detection of rosacea. The accuracy of classifying the three subtypes of rosacea, ETR, PPR, PhR was 83.9%, 74.3% and 80.0%, respectively. Moreover, the accuracy and precision of our CNN to distinguish rosacea from acne reached 0.931 and 0.893, respectively. For the identificaiton between rosacea, seborrheic dermatitis and eczema, the overall accuracy was 0.757 and the precision was 0.667. Finally, by comparing the CNN with different levels of dermatologists, we showed that our CNN system is capable of identifying rosacea with a performance superior to resident doctors or attending physicians and comparable to experienced specialists.

Conclusions:

In conclusion, by assessing clinical images, the CNN system in our study performed at dermatologist-level in the identification of rosacea. Clinical Trial: None


 Citation

Please cite as:

Zhao Z, Wu C, Zhang S, He F, Liu F, Wang B, Huang Y, Shi W, Jian D, Xie H, Yeh CY, Li J

A Novel Convolutional Neural Network for the Diagnosis and Classification of Rosacea: Usability Study

JMIR Med Inform 2021;9(3):e23415

DOI: 10.2196/23415

PMID: 33720027

PMCID: 8077711

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