Accepted for/Published in: JMIR Research Protocols
Date Submitted: Jun 5, 2020
Date Accepted: Aug 18, 2020
Self-collection for HPV-based cervical screening: Qualitative evidence synthesis and systematic review protocol
ABSTRACT
Background:
Cervical cancer is the fourth most common cancer affecting women worldwide. In the 1980s, it was found that the sexually transmitted disease, Human Papillomavirus ( or HPV), causes over 90% of all cervical cancer cases. Since that discovery, diagnostic technologies have been developed for the detection of HPV DNA in cervical samples. However, significant socio-cultural and structural barriers remain. Major strides have taken place in recent years to address these barriers, such as the self-collection for HPV-based cervical screening method.
Objective:
The purpose of this review is to synthesize qualitative evidence around the self-collection method and identify strategies to increase acceptability and feasibility in different settings. This qualitative synthesis will aim to better understand how to conceptualize and implement more effective, accessible and socially and culturally acceptable cervical screening programs and policies globally.
Methods:
A systematic search in the following databases will be conducted in Global Health, CINAHL (Cumulative Index to Nursing and Allied Health Literature), ERIC, ProQuest, Social Science Research Network, EMBASE, EMCARE, Medline (OVID), Scopus, Web of Science, and Google scholar. Both published/peer-reviewed articles and grey literature will be included. Two reviewers will independently screen and assess the studies. The data will be coded and analysed using a thematic synthesis process. The Socio Ecological Model (SEM) will be used to organize emergent themes at the micro and macro levels. The results will be presented in narrative and tabular form.
Results:
This review will involve the collection and analysis of publicly available secondary data, and therefore, does not require ethical approval. The review findings will be disseminated through publication in a peer-reviewed journal and scientific conference presentations.
Conclusions:
. The review will include relevant discussion points to further guide implementation researchers for the prevention of cervical cancer globally as well as implications for future research. Clinical Trial: This systematic review protocol is registered with the International Prospective Register of Systematic Reviews (PROSPERO). PROSPERO Registration Number: CRD42019109073
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Copyright
© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.