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Accepted for/Published in: JMIR Medical Informatics

Date Submitted: Jun 4, 2020
Date Accepted: Sep 16, 2020

The final, peer-reviewed published version of this preprint can be found here:

Institution-Specific Machine Learning Models for Prehospital Assessment to Predict Hospital Admission: Prediction Model Development Study

Shirakawa T, Sonoo T, Ogura K, Fujimori R, Hara K, Goto T, Hashimoto H, Takahashi Y, Naraba H, Nakamura K

Institution-Specific Machine Learning Models for Prehospital Assessment to Predict Hospital Admission: Prediction Model Development Study

JMIR Med Inform 2020;8(10):e20324

DOI: 10.2196/20324

PMID: 33107830

PMCID: 7655472

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Development of Machine Learning Models for Prehospital Assessment to Predict Hospital Admission

  • Toru Shirakawa; 
  • Tomohiro Sonoo; 
  • Kentaro Ogura; 
  • Ryo Fujimori; 
  • Konan Hara; 
  • Tadahiro Goto; 
  • Hideki Hashimoto; 
  • Yuji Takahashi; 
  • Hiromu Naraba; 
  • Kensuke Nakamura

ABSTRACT

Background:

Although multiple prediction models have been developed to predict hospital admission to emergency departments (EDs) to address overcrowding and patient safety, few studies have examined prediction models for prehospital use. Development of institution-specific prediction models is feasible in this age of data science, provided that predictor-related information is readily collectable.

Objective:

We aimed at developing a hospital admission prediction model based on patient information that is commonly available during ambulance transport before hospitalization.

Methods:

Patients transported by ambulance to our ED from April 2018 through March 2019 were enrolled. Candidate predictors were age, sex, chief complaint, vital signs, and patient medical history, all of which were recorded by emergency medical teams during ambulance transport. Patients were divided into two cohorts for derivation (70%) and validation (30%). For statistical models, logistic regression, logistic lasso, random forest, and gradient boosting machine were used. Prediction models were developed in the derivation cohort. Model performance was assessed by area under the receiver–operator characteristic curve (ROC–AUC) and association measures in the validation cohort.

Results:

Of 5145 patients transported by ambulance, including deaths in the ED and hospital transfers, 2699 (52.5%) required hospital admission. Prediction performance was higher according to the addition of predictive factors, attaining the best performance of an ROC–AUC of 0.818 (95% confidence interval 0.792–0.839) with a machine learning model and predictive factors of age, sex, chief complaint, and vital signs. Sensitivity and specificity of this model were, respectively, 0.744 (0.716–0.773) and 0.745 (0.709–0.776).

Conclusions:

For patients transferred to EDs, we developed a well-performing hospital admission prediction model based on prehospital information including chief complaints.


 Citation

Please cite as:

Shirakawa T, Sonoo T, Ogura K, Fujimori R, Hara K, Goto T, Hashimoto H, Takahashi Y, Naraba H, Nakamura K

Institution-Specific Machine Learning Models for Prehospital Assessment to Predict Hospital Admission: Prediction Model Development Study

JMIR Med Inform 2020;8(10):e20324

DOI: 10.2196/20324

PMID: 33107830

PMCID: 7655472

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