Accepted for/Published in: JMIR Diabetes
Date Submitted: May 19, 2020
Date Accepted: Feb 16, 2021
(closed for review but you can still tweet)
Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.
Telemetric Interventions offer new Opportunities managing Type 1 Diabetes Mellitus: A systematic meta-analysis
ABSTRACT
Background:
The prevalence of Diabetes mellitus (DM) increases rapidly worldwide. At the same time technological advances offer new opportunities for a better disease management targeting type 1 diabetes mellitus (T1DM) patients. Telemetry, the remote acquisition of patient data via a telecommunication system, is a promising field of application of Electronic Health (eHealth), and quickly growing in importance.
Objective:
We summarized the current evidence for the effectiveness of telemetric approaches in T1DM management. This systematic meta-review examined different types of interventions of the technologies used in communication between health care professionals and patients as well as their key outcomes.
Methods:
We performed a systematic search in Web of Science Core Collection, EMBASE, Cochrane Library, MEDLINE via PubMed, and CINAHL databases in April 2020 with regard to the effectiveness of telemetric interventions in T1DM patients. We classified the interventions in four categories according to the technology used: (1) “real-time video communication” (2) “real-time audio communication” (3) “asynchronous communication” and (4) “combined forms of communication” (real-time and asynchronous). We considered various study designs such as systematic reviews (SRs), clinical trials (CT), meta-analysis (MAs), randomized controlled trials (RCTs), and focussed on key outcomes.
Results:
We identified n=23 eligible publications in total: RCTs (n=15), SRs and MAs (n=5), cohort studies (n=2), and one qualitative publication (n=1). Of n=17 studies, nine (52,9%) indicated a significant decline in HbA1c levels. 60,8% (n=14) reported overall (mildly) positive effects in terms of telemetric interventions by addressing all measured outcomes. Moreover, “asynchronous interventions” were most successful for patients diagnosed with T1DM, but no technology was clearly superior. However, there were many nonsignificant results, not sustained effects, and in some studies, the control group benefited from telemetric support or increased frequency of contacts.
Conclusions:
This systematic meta-review shows significant reduction in HbA1c levels and reports overall positive effects of telemedical interventions in T1DM. However, the whole potential of telemetric approaches in T1DM management should be analysed in detail in further studies since the evidence seems to be inconsistent regarding different outcomes and type of interventions. Clinical Trial: A systematic Meta-Review.
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