Accepted for/Published in: Journal of Medical Internet Research
Date Submitted: Mar 31, 2020
Date Accepted: May 14, 2020
Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.
A Clinical Observational Study of a Mobile Health Application for Japanese Adult Patients with Asthma
ABSTRACT
Background:
Inappropriate asthma control reduces quality of life and causes increased exacerbations. Mobile health (mHealth) employs information and communication technology for surveying health-related matters.
Objective:
This non-interventional, observational study assessed current real-world asthma control levels among Japanese patients with asthma and cough-variant asthma (CVA) using our Zensoku-Log application (app).
Methods:
We developed the app using the ResearchKit platform and conducted a mobile-based, self-reporting, observational survey among patients with asthma and CVA. The app was downloaded 7,855 times between February 2016 and February 2018, and enabled collection of data on symptoms, comorbidities, quality of life, medications, asthma control, and adherence.
Results:
Of 1,744 participants (median age: 33 years; range: 20–74 years; male:female ratio 38.7:61.3), 51% attended unscheduled visits, 62.8% attended regularly scheduled visits, 23% smoked, and 41% had pets. Over 90% of participants had atopic predisposition, including allergic rhinitis and atopic dermatitis. Daily inhaled corticosteroid and oral corticosteroid had been prescribed for 90% and 20% of participants, respectively. Despite an asthma control questionnaire demonstrated poor asthma control in 59%, a leukotriene receptor antagonist, theophylline, and a long-acting muscarinic antagonist had been prescribed for only 31%, 16%, and 4%, respectively. The Adherence Starts with Knowledge-12 total score was 29. In 421 participants who repeated the questionnaire, asthma control increased significantly between the first and last answers (p = 0.002).
Conclusions:
Users of this mHealth app in Japan had poorly controlled asthma and may need more treatment for asthma and their comorbidities. Repeated app users demonstrated improved asthma control. Clinical Trial: This study was registered in the UMIN Clinical Trial Registry (UMIN000021043) on February 16th, 2016 (http://www.umin.ac.jp/).
Citation
Request queued. Please wait while the file is being generated. It may take some time.
Copyright
© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.