Accepted for/Published in: JMIR mHealth and uHealth
Date Submitted: Mar 23, 2020
Date Accepted: Sep 2, 2020
Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.
Evaluation of the MoMba Live Long® Smartphone-Based System: Towards Remote Assessment of Smoking Status Through Breath in the Perinatal Period.
ABSTRACT
Background:
The smoking relapse rate during the first 12 months after pregnancy is around 80%. Delivering remote smoking cessation interventions to women in the postpartum period can reduce the burden associated with frequent office visits and enable remote communication and support. Developing reliable remote smoking measuring instruments is a crucial step in achieving this vision.
Objective:
The study presents the development and evaluation of the MoMba Live Long® System, a smartphone-based breath carbon monoxide (CO) meter and a custom smartphone application for smoking cessation interventions using contingency management (CM) remotely.
Methods:
In-office breath tests were completed using both the MoMba Live Long System and a commercial monitor, piCO+ Smokerlyzer. Each participant also provided a urine test at each in-office breath test for smoking status validation through cotinine urine tests. Ten pregnant adult women participated in the MoMba Live Long pilot study for a period of 12 weeks.
Results:
Analyses included 143 breath tests contributed from 10 participants. Significant CO reading correlations (r=0.88) were observed between the MoMba Live Long System and the piCO+. In addition, the MoMba Live Long system accurately distinguished smokers from non-smokers with a sensitivity of 0.91 and specificity of 0.94 when the piCO+ was used as a gold standard and a sensitivity of 0.81 and specificity of 1.00 when quantitative cotinine in urine was used to confirm smoking status.
Conclusions:
Relatively inexpensive portable and internet-connected CO monitors can enable remote smoking status detection in a wide variety of non-clinical settings with reliable and valid measures comparable to the ones obtained with a commercially available CO monitor. Clinical Trial: NCI grant 5R01CA195654
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