Previously submitted to: JMIR Medical Informatics (no longer under consideration since Sep 09, 2021)
Date Submitted: Mar 5, 2020
Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.
Effect of Statins on Patients with Acute Ischemic Stroke Infection based on Intelligent Data Acquisition of Computed Tomography Image information
ABSTRACT
To reduce the infection rate in patients with acute ischemic stroke, effect of statins on patients with acute ischemic stroke infection based on intelligent data acquisition of computed tomography image information was investigated. In this study, 122 infected patients with acute ischemic stroke in our hospital from June 2016 to December 2018 were included as subjects, and they were divided into experimental group (statin treatment) and control group (non-statin treatment). On admission, the differences in baseline data, stroke classification, neurological impairment, and the number of affected cerebral lobes between the two groups were compared; the probability of pulmonary, urinary system, and co-infection in patients with different stroke types was compared; the modified Rankin score and pap scale were used to evaluate the prognosis of patients; FBP and iDose4 algorithms were used to reconstruct CT images of stroke patients, and the differences in noise and Signal to Noise Ratio (SNR) of reconstructed images by different algorithms were compared; CT images were used to qualitatively and quantitatively analyze the imaging characteristics of stroke patients and the affected cerebral lobes. The results showed that the proportion of TACI in the control group was significantly higher than that in the control group (P<0.01); the incidence of pulmonary infection in patients with TACI typing in the control group was significantly higher than that in the experimental group (P<0.01); the scale scores of the experimental group at 0, 1, and 2 months were significantly higher than those of the control group (P<0.05); the noise in the image reconstructed by iDose4 method was significantly lower than that by FBP method (P<0.01); there were statistically significant differences between the control group and the experimental group in the proportion of involvement in the right parietal lobe, left insula, left internal capsule, subcortex, and right brain stem (P<0.05), which showed that statins could effectively improve the prognosis of patients with acute stroke.
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