Previously submitted to: JMIR Cancer (no longer under consideration since Nov 26, 2021)
Date Submitted: Feb 22, 2020
Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.
A clinicopathological study on laryngeal cancer
ABSTRACT
Background:
The study was conducted at Governemnt Rajaji Hospital
Objective:
Laryngeal cancer is primarily a disease of middle aged men. It has peak incidence in the seventh decade. Worldwide it is the common head and neck cancer. Squamous cell carcinoma is the most common type of tumor, comprising 90 percent or more of all laryngeal malignancies. Laryngeal cancer is more common in areas with higher levels of social poverty. The study is done to find out the common clinical presentation of patients with laryngeal carcinoma with reference to the age profile, the symptomatology, disease stage, etiological factors, occupational history, histological profile and to determine the treatment modalities offered to the laryngeal cancer patients attending ENT OPD at GRH., Madurai.
Methods:
This is a hospital based prospective study. The study was conducted at Government Rajaji Hospital.,Madurai.,India.All the newly diagnosed laryngeal cancer patients were included in the study between July 2013 to June 2014.Totaly we had 113 patients in this study.
Results:
In our study most of them were male patients. The most common age group Was 65 years.We had only 4 female patients in our study and all had supraglottic growth. All the patients belonged to low socioeconomic strata.The most common part of larynx involved is supraglottis. None of our patients had distant metastasis. The most common presentation was difficulty in breathing and stridor, later followed by change of voice and dysphagia.The common histopathological finding was squmous cell carcinoma. In that moderatelty differentiated was the most common type.The most common stage was stage III. The most common treatment offered at our hospital was concurrent chemoradiotherapy.
Conclusions:
Diagnosis of laryngeal cancer is based on good history, clinical examination, direct examination of the larynx, CT scan and supported by histopathological examination. This study has been done to increase awareness on early diagnosis and treatment which leads to the better life style of the laryngeal cancer patients.
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