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Accepted for/Published in: JMIR Serious Games

Date Submitted: Feb 21, 2020
Date Accepted: Aug 11, 2021

The final, peer-reviewed published version of this preprint can be found here:

Dissecting Digital Card Games to Yield Digital Biomarkers for the Assessment of Mild Cognitive Impairment: Methodological Approach and Exploratory Study

Gielis K, De Croon R, Dierick P, Brito F, Van Assche L, Tournoy J, Vanden Abeele V

Dissecting Digital Card Games to Yield Digital Biomarkers for the Assessment of Mild Cognitive Impairment: Methodological Approach and Exploratory Study

JMIR Serious Games 2021;9(4):e18359

DOI: 10.2196/18359

PMID: 34734825

PMCID: 8603181

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

An Expert Consensus Study on the Validity of Card Games to Assess Mild Cognitive Impairment

  • Karsten Gielis; 
  • Robin De Croon; 
  • Paul Dierick; 
  • Filipa Brito; 
  • Lies Van Assche; 
  • Jos Tournoy; 
  • Vero Vanden Abeele

ABSTRACT

Background:

Mild Cognitive Impairment, the intermediate cognitive status between healthy cognitive decline and pathological decline, is an important clinical construct for signaling possible prodromes of dementia. Unfortunately, there is an underdetection of this condition. To provide monitoring and screening, commercial off-the-shelf video games may be of interest. They maintain player engagement over a longer period of time and support longitudinal measurements of cognitive performance.

Objective:

This paper aims to explore how player actions of Klondike Solitaire relate to cognitive functions and to which extent they are indicative of Mild Cognitive Impairment.

Methods:

Eleven experts in the domain of cognitive impairments were asked to correlate 21 player actions to eleven cognitive functions. Expert agreement was verified through intraclass correlation, based on a two-way fully crossed design with type consistency.

Results:

All intraclass correlations for player actions and cognitive function scored above 0.75, indicating good to excellent reliability. Further scrutinizing of the results revealed that all player actions had at least one cognitive function which was on average moderately to strongly correlated to a cognitive function. Similarly, each cognitive function had at least one player action which was on average moderately to strongly correlated. Similarities and patterns were found amongst player actions, providing insight into the mechanics of Klondike Solitaire gameplay.

Conclusions:

Together, these results suggest that Klondike Solitaire has potential as a complementary tool for screening and monitoring cognition, warranting further research which analyses Klondike Solitaire gameplay data of older adults with mild cognitive impairment.


 Citation

Please cite as:

Gielis K, De Croon R, Dierick P, Brito F, Van Assche L, Tournoy J, Vanden Abeele V

Dissecting Digital Card Games to Yield Digital Biomarkers for the Assessment of Mild Cognitive Impairment: Methodological Approach and Exploratory Study

JMIR Serious Games 2021;9(4):e18359

DOI: 10.2196/18359

PMID: 34734825

PMCID: 8603181

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