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Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Dec 10, 2019
Date Accepted: Aug 25, 2020

The final, peer-reviewed published version of this preprint can be found here:

Virtual Reality Relaxation for Patients With a Psychiatric Disorder: Crossover Randomized Controlled Trial

Virtual Reality Relaxation for Patients With a Psychiatric Disorder: Crossover Randomized Controlled Trial

J Med Internet Res 2021;23(1):e17233

DOI: 10.2196/17233

PMID: 33448933

PMCID: 7846446

Virtual Reality relaxation for patients with a psychiatric disorder: cross-over randomized controlled trial

ABSTRACT

Background:

Stress management is a cornerstone of psychiatric treatments. However, stress-reducing interventions (e.g., relaxation exercises) are challenging for people with mental health problems. We developed a virtual reality (VR) self-management relaxation tool with immersive 360o nature videos and interactive animated elements.

Objective:

To investigate the immediate and short-term effects of VR relaxation (VRelax) on stress level, mood states and symptoms in patients with a psychiatric disorder, compared to standard relaxation exercises.

Methods:

A randomized cross-over trial was conducted in 50 patients receiving ambulatory treatment for anxiety, psychotic, depressive or bipolar disorder. Participants were randomly assigned to start with VRelax or standard relaxation, and used both interventions for 10 days at home. They completed Visual Analogue Scales (VAS) of stress level and mood states before and after each session. Global perceived stress and psychiatric symptoms were measured before and after both intervention periods. Treatment effects were analyzed with multilevel repeated-measures regression models and two-way ANOVA.

Results:

Both VRelax and standard relaxation exercises led to a statistically significant immediate reduction of stress and improvement of mood states. Compared to standard relaxation, VRelax resulted in a significantly greater immediate improvement of anxiety (B=-4.30, 95%CI=-5.86;-2.73), sadness (B=-3.65, 95%CI =-5.39;-1.91), cheerfulness (B=3.67, 95%CI=2.15;5.18), overall positive mood (B=7.59, 95%CI=2.28;12.89), and overall negative mood (B=10.88, 95%CI=5.89;15.87). There were no significant differences between short-term effects of the two treatments on symptoms and global perceived stress.

Conclusions:

If the results of this trial are replicated and extended, VRelax may provide a much needed effective self-management stress intervention to enhance psychiatric treatments. Clinical Trial: Dutch trial register, number NTR 7294.


 Citation

Please cite as:

Virtual Reality Relaxation for Patients With a Psychiatric Disorder: Crossover Randomized Controlled Trial

J Med Internet Res 2021;23(1):e17233

DOI: 10.2196/17233

PMID: 33448933

PMCID: 7846446

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