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Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Aug 16, 2019
Date Accepted: Mar 23, 2020

The final, peer-reviewed published version of this preprint can be found here:

Reliability of Smartphone for Diffusion-Weighted Imaging–Alberta Stroke Program Early Computed Tomography Scores in Acute Ischemic Stroke Patients: Diagnostic Test Accuracy Study

Sakai K, Komatsu T, Iguchi Y, Takao H, Ishibashi T, Murayama Y

Reliability of Smartphone for Diffusion-Weighted Imaging–Alberta Stroke Program Early Computed Tomography Scores in Acute Ischemic Stroke Patients: Diagnostic Test Accuracy Study

J Med Internet Res 2020;22(6):e15893

DOI: 10.2196/15893

PMID: 32515744

PMCID: 7312257

Reliability of Assessment of Neuroimaging by Smartphone for Diffusion Weighted Imaging–Alberta Stroke Program Early Computed Tomography Scores in Acute Ischemic Stroke Patients

  • Kenichiro Sakai; 
  • Teppei Komatsu; 
  • Yasuyuki Iguchi; 
  • Hiroyuki Takao; 
  • Toshihiro Ishibashi; 
  • Yuichi Murayama

ABSTRACT

Background:

High-quality neuroimages can be viewed via a medical app installed on a smartphone. Although inter-device agreement between smartphone and desktop PC monitor was found to be favorable for evaluating CT images, there are no inter-device agreement data for DWI.

Objective:

Our objective is to investigate the diagnostic accuracy and interrater agreement of Diffusion-weighted Imaging–Alberta Stroke Program Early Computed Tomography Scores (DWI-ASPECTS) in acute ischemic stroke patients for neuroimages evaluated on a smartphone app and on a desktop PC monitor.

Methods:

The ischemic change in the DWI of consecutive patients with acute stroke in the MCA territory was graded by two vascular neurologists via a JOIN smartphone app and a desktop PC monitor. The vascular neurologists were blinded to all patient information. Each image was categorized as either DWI-ASPECTS ≥7 or DWI-ASPECTS <7 according to the Japan Society for Neuroendovascular Therapy. We analyzed inter-device agreement and inter-rater agreement with respect to DWI-ASPECTS. Elapsed interpretation time was compared between DWI-ASPECTS evaluated by JOIN smartphone app and that by desktop PC monitor.

Results:

We analyzed the images of 111 patients (66% male, median age, 69 years; median NIHSS score on admission, 4). Inter-device agreement regarding DWI-ASPECTS between the smartphone and the desktop PC monitor was favorable agreement (vascular neurologist 1; kappa = 0.777, p<0.001, vascular neurologist 2; kappa = 0.787, p < 0.001). Inter-rater agreement was also satisfactory for the smartphone (kappa = 0.710, p < 0.001), and the desktop PC monitor (kappa = 0.663, p < 0.001). Median elapsed interpretation time was similar between the smartphone and the desktop PC monitor (vascular neurologist 1, 1.7 vs. 1.6 min (p = 0.64); and vascular neurologist 2, 2.4 vs. 2.0 min (p = 0.14).

Conclusions:

The use of a smartphone app enables vascular neurologists to estimate DWI-ASPECTS accurately and rapidly. The JOIN medical smartphone app shows great promise in the management of acute stroke.


 Citation

Please cite as:

Sakai K, Komatsu T, Iguchi Y, Takao H, Ishibashi T, Murayama Y

Reliability of Smartphone for Diffusion-Weighted Imaging–Alberta Stroke Program Early Computed Tomography Scores in Acute Ischemic Stroke Patients: Diagnostic Test Accuracy Study

J Med Internet Res 2020;22(6):e15893

DOI: 10.2196/15893

PMID: 32515744

PMCID: 7312257

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