Accepted for/Published in: JMIR Research Protocols
Date Submitted: Aug 13, 2019
Date Accepted: Nov 5, 2019
Date Submitted to PubMed: Jun 8, 2020
Morbidity Prevalence Estimate at Six Months Following a Stroke (MORe PREcISE): Protocol for a Cohort Study
ABSTRACT
Background:
The prevalence of morbidity secondary to stroke is important to healthcare professionals, healthcare commissioners, third sector organisations and stroke survivors to understand the likely progress of post-stroke sequelae and to aid in commissioning decisions, care planning and adjusting to life after stroke.
Objective:
The primary aim of the study is to determine the prevalence of morbidity secondary to a stroke, predictors of morbidity and trends in domains such as quality of life (QoL) and functional status using patient-reported outcomes, cognitive and functional assessments.
Methods:
500 participants will be recruited across Wales and England within 14 days following an admission to a stroke unit with either an ischaemic or haemorrhagic stroke as part of a multicentre cohort study. Participants are assessed at baseline ≤14 days post stroke and subsequently at 90 (±14 days) and 180 (±14 days) post-stroke. At each time point a range of data will be collected relating to the following domains; demographic, routine clinical, patient-reported, cognitive status, emotional well-being and functional ability.
Results:
Recruitment commenced in October 2018 with 19 sites open as of May 2019 and recruitment set to close 31st October 2019
Conclusions:
The primary outcome is the prevalence of morbidity at six months secondary to a stroke. Further analysis will consider temporal changes in the health-related domains to describe trends between baseline, 3 months and 6-month time points. Clinical Trial: ClinicalTrials.gov NCT03605381
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