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Accepted for/Published in: JMIR Research Protocols

Date Submitted: Mar 28, 2019
Date Accepted: Aug 14, 2019

The final, peer-reviewed published version of this preprint can be found here:

Feasibility of Point-of-Care Testing for Influenza Within a National Primary Care Sentinel Surveillance Network in England: Protocol for a Mixed Methods Study

de Lusignan S, Hoang U, Liyanage H, Yonova I, Ferreira F, Diez-Domingo J, Clark T

Feasibility of Point-of-Care Testing for Influenza Within a National Primary Care Sentinel Surveillance Network in England: Protocol for a Mixed Methods Study

JMIR Res Protoc 2019;8(11):e14186

DOI: 10.2196/14186

PMID: 31710303

PMCID: 6878097

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Feasibility of Point-of-Care Testing for Influenza Within a National Primary Care Sentinel Surveillance Network in England: Protocol for a Mixed Methods Study

  • Simon de Lusignan; 
  • Uy Hoang; 
  • Harshana Liyanage; 
  • Ivelina Yonova; 
  • Filipa Ferreira; 
  • Javier Diez-Domingo; 
  • Tristan Clark

Background:

Point-of-care testing (POCT) for influenza promises to provide real-time information to influence clinical decision making and improve patient outcomes. Public Health England has published a toolkit to assist implementation of these tests in the UK National Health Service.

Objective:

A feasibility study will be undertaken to assess the implementation of influenza POCT in primary care as part of a sentinel surveillance network.

Methods:

We will conduct a mixed methods study to compare the sampling rates in practices using POCT and current virology swabbing practices not using POCT, and to understand the issues and barriers to implementation of influenza POCT in primary care workflows. The study will take place between March and May 2019. It will be nested in general practices that are part of the English national sentinel surveillance network run by the Royal College of General Practitioners Research and Surveillance Centre. The primary outcome is the number of valid influenza swabs taken and tested by the practices involved in the study using the new POCT.

Results:

A total of 6 practices were recruited, and data collection commenced on March 11, 2019. Moreover, 312 swab samples had been collected at the time of submission of the protocol, which was 32.5% (312/960) of the expected sample size. In addition, 68 samples were positive for influenza, which was 20.1% (68/338) of the expected sample size.

Conclusions:

To the best of our knowledge, this is the first time an evaluation study has been undertaken on POCT for influenza in general practice in the United Kingdom. This proposed study promises to shed light on the feasibility of implementation of POCT in primary care and on the views of practitioners about the use of influenza POCT in primary care, including its impact on primary care workflows.

International Registered Report:

DERR1-10.2196/14186


 Citation

Please cite as:

de Lusignan S, Hoang U, Liyanage H, Yonova I, Ferreira F, Diez-Domingo J, Clark T

Feasibility of Point-of-Care Testing for Influenza Within a National Primary Care Sentinel Surveillance Network in England: Protocol for a Mixed Methods Study

JMIR Res Protoc 2019;8(11):e14186

DOI: 10.2196/14186

PMID: 31710303

PMCID: 6878097

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