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Accepted for/Published in: JMIR mHealth and uHealth

Date Submitted: Feb 22, 2019
Open Peer Review Period: Feb 25, 2019 - Mar 1, 2019
Date Accepted: Jul 7, 2019
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

A Mobile Phone App Featuring Cue Exposure Therapy As Aftercare for Alcohol Use Disorders: An Investigator-Blinded Randomized Controlled Trial

Mellentin AI, Nielsen B, Nielsen AS, Yu F, Nielsen D, Mejldal A, Stenager E

A Mobile Phone App Featuring Cue Exposure Therapy As Aftercare for Alcohol Use Disorders: An Investigator-Blinded Randomized Controlled Trial

JMIR Mhealth Uhealth 2019;7(8):e13793

DOI: 10.2196/13793

PMID: 31420960

PMCID: 6716334

A smartphone application featuring cue exposure therapy as aftercare for alcohol use disorders: a randomized controlled trial

  • Angelina Isabella Mellentin; 
  • Bent Nielsen; 
  • Anette Søgaard Nielsen; 
  • Fei Yu; 
  • Dorthe Nielsen; 
  • Anna Mejldal; 
  • Elsebeth Stenager

ABSTRACT

Background:

Cue exposure therapy (CET) is a psychological approach developed to prepare individuals with alcohol use disorder (AUD) for confronting alcohol and associated stimuli in real life. CET has shown promise when treating AUD in group sessions, but it is unknown whether progressing from group sessions to using a smartphone application is an effective delivery pathway.

Objective:

The objectives of this study were: 1) to investigate whether CET as aftercare increases the effectiveness of primary treatment with cognitive behavior therapy (CBT), and 2) to investigate whether CET delivered by means of a smartphone application is similarly effective compared to CET group sessions.

Methods:

The objectives of this study were: 1) to investigate whether CET as aftercare increases the effectiveness of primary treatment with cognitive behavior therapy (CBT), and 2) to investigate whether CET delivered by means of a smartphone application is similarly effective compared to CET group sessions.

Results:

A total of 153 individuals (93%) completed both the post-treatment and 6-month follow-up assessment. No differences in the trajectories were found between the experimental groups (CET GA and SAA) compared to AAU on drinking- and craving outcomes over time. Both the CET GA group (Est.= 5.99, SE 2.59, z=2.31, p= 0.021) and the CET SAA group (Est.=4.90, SE= 2.26, z=2.31, p= 0.021) showed increased use of the USCS compared to AAU at post-treatment, but the effect attenuated at the 6-month follow-up. Finally, no differences were detected between the experimental groups on any outcomes.

Conclusions:

Neither CET with USCS delivered via group session, nor a smartphone application as aftercare, increased the effectiveness of primary treatment in the present study. This is the first study to show that CET with USCS may not be an effective psychological approach. Clinical Trial: ClinicalTrials.gov ID: NCT02298751


 Citation

Please cite as:

Mellentin AI, Nielsen B, Nielsen AS, Yu F, Nielsen D, Mejldal A, Stenager E

A Mobile Phone App Featuring Cue Exposure Therapy As Aftercare for Alcohol Use Disorders: An Investigator-Blinded Randomized Controlled Trial

JMIR Mhealth Uhealth 2019;7(8):e13793

DOI: 10.2196/13793

PMID: 31420960

PMCID: 6716334

Per the author's request the PDF is not available.

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