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Accepted for/Published in: JMIR mHealth and uHealth

Date Submitted: Feb 18, 2019
Open Peer Review Period: Feb 21, 2019 - Apr 18, 2019
Date Accepted: Feb 22, 2020
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Derivation of Breathing Metrics From a Photoplethysmogram at Rest: Machine Learning Methodology

Prinable J, Jones P, Boland D, Thamrin C, McEwan A

Derivation of Breathing Metrics From a Photoplethysmogram at Rest: Machine Learning Methodology

JMIR Mhealth Uhealth 2020;8(7):e13737

DOI: 10.2196/13737

PMID: 32735229

PMCID: 7428909

Derivation of breathing metrics from a photoplethysmograph at rest

  • Joseph Prinable; 
  • Peter Jones; 
  • David Boland; 
  • Cindy Thamrin; 
  • Alistair McEwan

ABSTRACT

Background:

Abstract—Recently, there has been an increased interest in monitoring health using wearable sensors technologies however, few have focused on breathing. The ability to monitor breathing metrics may have indications both for general health as well as respiratory conditions such as asthma, where long-term monitoring of lung function has shown promising utility.

Objective:

In this paper we characterise a Long Short-Term Memory (LSTM) architecture and predict measures of inter-breath intervals, respiratory rate and the inspiration:expiration ratio from a photoplethsymogram signal.

Methods:

A pulse oximeter was mounted to the left index finger of nine healthy subjects who breathed at controlled respiratory rates. A respiratory band was used to collect a reference signal as a comparison.

Results:

Over a 40 second window the LSTM model predicted breathing metrics with a bias and 95% confidence interval for inspiration time 0.03 s (-1.14, 1.20), expiration time 0.05 s (-1.07, 0.96), respiratory rate 0.12 (-1.5,1.75), inter-breath intervals (-1.29, 1.16) and the I:E ratio 0.00 (-.45, 0.46).

Conclusions:

A trained LSTM model shows acceptable accuracy for deriving breathing metrics, and could be useful for long-term breathing monitoring in health. Its utility in respiratory disease, e.g. asthma warrants further investigation. Clinical Trial: Sydney Local Health District Human Research Ethics Committee (#LNR/16/HAWKE99 ethics approval).


 Citation

Please cite as:

Prinable J, Jones P, Boland D, Thamrin C, McEwan A

Derivation of Breathing Metrics From a Photoplethysmogram at Rest: Machine Learning Methodology

JMIR Mhealth Uhealth 2020;8(7):e13737

DOI: 10.2196/13737

PMID: 32735229

PMCID: 7428909

Per the author's request the PDF is not available.

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