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Accepted for/Published in: JMIR Public Health and Surveillance

Date Submitted: Dec 20, 2018
Open Peer Review Period: Dec 31, 2018 - Feb 25, 2019
Date Accepted: Aug 2, 2019
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

The Association Between Internet Searches and Moisturizer Prescription in Japan: Retrospective Observational Study

Mimura W, Akazawa M

The Association Between Internet Searches and Moisturizer Prescription in Japan: Retrospective Observational Study

JMIR Public Health Surveill 2019;5(4):e13212

DOI: 10.2196/13212

PMID: 31596248

PMCID: 6812878

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

The Association Between Internet Searches and Moisturizer Prescription in Japan: Retrospective Observational Study

  • Wataru Mimura; 
  • Manabu Akazawa

Background:

Heparinoid is a medication prescribed in Japan for skin diseases, such as atopic dermatitis and dry skin. Heparinoid prescription has increased with instances of internet blogs recommending its use as a cosmetic.

Objective:

This study aimed to examine the prescription trends in moisturizer use and analyze their association with internet searches.

Methods:

We used a claims database to identify pharmacy claims of heparinoid-only prescriptions in Japan. Additionally, we used Google Trends to obtain internet search data for the period between October 1, 2007, and September 31, 2017. To analyze the association between heparinoid prescriptions and internet searches, we performed an autoregressive integrated moving average approach for each time series.

Results:

We identified 155,733 patients who had been prescribed heparinoid. The number of prescriptions increased from 2011 onward, and related internet searches increased from 2012 onward. Internet searches were significantly correlated with total heparinoid prescription (correlation coefficient=.25, P=.005). In addition, internet searches were significantly correlated with heparinoid prescription in those aged 20-59 years at –1-month lag in Google Trends (correlation coefficient=.30, P=.001).

Conclusions:

Google searches related to heparinoid prescriptions showed a seasonal pattern and increased gradually over the preceding several years. Google searches were positively correlated with prescription trends. In addition, in a particular age group (20-59 years), prescriptions increased with the increase in internet searches. These results suggest that people obtained health-related information on the internet and that this affected their behavior and prescription requests.


 Citation

Please cite as:

Mimura W, Akazawa M

The Association Between Internet Searches and Moisturizer Prescription in Japan: Retrospective Observational Study

JMIR Public Health Surveill 2019;5(4):e13212

DOI: 10.2196/13212

PMID: 31596248

PMCID: 6812878

Per the author's request the PDF is not available.

© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.