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Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Oct 15, 2018
Open Peer Review Period: Oct 23, 2018 - Dec 18, 2018
Date Accepted: May 11, 2019
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Mobile Apps for Increasing Treatment Adherence: Systematic Review

Pérez-Jover V, Sala-González M, Guilabert M, Mira JJ

Mobile Apps for Increasing Treatment Adherence: Systematic Review

J Med Internet Res 2019;21(6):e12505

DOI: 10.2196/12505

PMID: 31215517

PMCID: 6604503

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Mobile Apps for Increasing Treatment Adherence: Systematic Review

  • Virtudes Pérez-Jover; 
  • Marina Sala-González; 
  • Mercedes Guilabert; 
  • José Joaquín Mira

Background:

It is estimated that 20% to 50% of patients do not take their medication correctly, and this leads to increased morbidity and inefficacy of therapeutic approaches. Fostering treatment adherence is a priority objective for all health systems. The growth of mobile apps to facilitate therapeutic adherence has significantly increased in recent years. However, the effectiveness of the apps for this purpose has not been evaluated.

Objective:

This study aimed to analyze whether mobile apps are perceived as useful for managing medication at home and if they actually contribute to increasing treatment adherence in patients.

Methods:

We carried out a systematic review of research published using Scopus, Cochrane Library, ProQuest, and MEDLINE databases and analyzed the information about their contribution to increasing therapeutic adherence and the perceived usefulness of mobile apps. This review examined studies published between 2000 and 2017.

Results:

Overall, 11 studies fulfilled the inclusion criteria. The sample sizes of these studies varied between 16 and 99 participants. In addition, 7 studies confirmed that the mobile app increased treatment adherence. In 5 of them, the before and after adherence measures suggested significant statistical improvements, when comparing self-reported adherence and missed dose with a percentage increase ranging between 7% and 40%. The users found mobile apps easy to use and useful for managing their medication. The patients were mostly satisfied with their use, with an average score of 8.1 out of 10.

Conclusions:

The use of mobile apps helps increase treatment adherence, and they are an appropriate method for managing medication at home.


 Citation

Please cite as:

Pérez-Jover V, Sala-González M, Guilabert M, Mira JJ

Mobile Apps for Increasing Treatment Adherence: Systematic Review

J Med Internet Res 2019;21(6):e12505

DOI: 10.2196/12505

PMID: 31215517

PMCID: 6604503

Per the author's request the PDF is not available.

© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.