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Accepted for/Published in: JMIR Formative Research

Date Submitted: Sep 22, 2018
Date Accepted: Oct 28, 2020
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Effectiveness of Text Message Reminders on Adherence to Inhaled Therapy in Patients With Asthma: Prospective Multicenter Randomized Clinical Trial

Almonacid C, Melero C, López Viña A, Cisneros C, Pérez de Llano L, Plaza V, García-Rivero JL, Romero Falcón A, Ramos J, Bazús González T, Andrés Prado M, Muriel A

Effectiveness of Text Message Reminders on Adherence to Inhaled Therapy in Patients With Asthma: Prospective Multicenter Randomized Clinical Trial

JMIR Form Res 2021;5(2):e12218

DOI: 10.2196/12218

PMID: 33560235

PMCID: 7902182

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Effectiveness of Text Message Reminders on Adherence to Inhaled Therapy in Patients With Asthma: Prospective Multicenter Randomized Clinical Trial

  • Carlos Almonacid; 
  • Carlos Melero; 
  • Antolín López Viña; 
  • Carolina Cisneros; 
  • Luis Pérez de Llano; 
  • Vicente Plaza; 
  • Juan Luis García-Rivero; 
  • Auxiliadora Romero Falcón; 
  • Jacinto Ramos; 
  • Teresa Bazús González; 
  • María Andrés Prado; 
  • Alfonso Muriel

Background:

Poor adherence to inhaled medication in asthma patients is of great concern. It is one of the main reasons for inadequate asthma control.

Objective:

The goal of the research was to determine if motivational messages using short message service (SMS, or text) improved adherence to inhaled medication in patients with asthma.

Methods:

A prospective multicenter randomized parallel-group clinical trial was conducted in 10 asthma clinics in Spain. Adherence was assessed with electronic monitors (Smartinhaler, Adherium Ltd) connected to inhalers. Patients in the SMS group received psychologist-developed motivational messages every 3 days for 6 months.

Results:

There were 53 patients in the SMS group and 88 patients in the control group. After 6 months, mean electronic adherence was 70% (SD 17%) in the intervention group and 69% (SD 17%) in the control group (P=.82). Significant differences between the study groups in morning and evening adherence to inhaled therapy, asthma control, exhaled nitric oxide levels, or improvement of lung functions were not observed.

Conclusions:

Motivational messages were not useful to improve adherence to inhaled asthma medication compared with usual care.


 Citation

Please cite as:

Almonacid C, Melero C, López Viña A, Cisneros C, Pérez de Llano L, Plaza V, García-Rivero JL, Romero Falcón A, Ramos J, Bazús González T, Andrés Prado M, Muriel A

Effectiveness of Text Message Reminders on Adherence to Inhaled Therapy in Patients With Asthma: Prospective Multicenter Randomized Clinical Trial

JMIR Form Res 2021;5(2):e12218

DOI: 10.2196/12218

PMID: 33560235

PMCID: 7902182

Per the author's request the PDF is not available.