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Accepted for/Published in: JMIR Formative Research

Date Submitted: Sep 22, 2018
Date Accepted: Oct 28, 2020
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Effectiveness of Text Message Reminders on Adherence to Inhaled Therapy in Patients With Asthma: Prospective Multicenter Randomized Clinical Trial

Almonacid C, Melero C, López-Viña A, Cisneros C, Pérez-Llano L, Plaza V, García-Rivero JL, Romero MA, Ramos-González J, Bazús T, Andres-Prado MJ, Muriel A

Effectiveness of Text Message Reminders on Adherence to Inhaled Therapy in Patients With Asthma: Prospective Multicenter Randomized Clinical Trial

JMIR Form Res 2021;5(2):e12218

DOI: 10.2196/12218

PMID: 33560235

PMCID: 7902182

Effectiveness of SMS (text message) reminders on adherence to inhaled therapy in patients with asthma: a prospective multicenter randomized clinical trial.

  • Carlos Almonacid; 
  • Carlos Melero; 
  • Antolin López-Viña; 
  • Carolina Cisneros; 
  • Luis Pérez-Llano; 
  • Vicente Plaza; 
  • Juan Luis García-Rivero; 
  • María Auxiliadora Romero; 
  • Jacinto Ramos-González; 
  • Teresa Bazús; 
  • Maria Jose Andres-Prado; 
  • Alfonso Muriel

ABSTRACT

Background:

Poor adherence to inhaled medication in asthma patients is of great concern due to the impact on poor asthma control resulting in more exacerbations and increasing the healthcare and economic burden of the disease.

Objective:

To determine in patients with asthma adequately treated and followed regularly, if a minimal intervention such as sending SMS text message reminders improved adherence to inhaled medication.

Methods:

A prospective randomized parallel-group and multicenter study was conducted in the outpatient clinics of specialized asthma units from the pneumology services of ten acute-care hospitals throughout Spain. Adherence was assessed with Smartinhaler™ connected to their current devices. Patients in the SMS group received reminders every 3 days for 6 months.

Results:

There were 53 patients in the SMS group and 88 controls. After 6 months, the mean (SD) electronic adherence was 70% (17%) in the intervention group and 69% (17%) in the control group (P = 0.817). Significant differences between the study groups in the percentages morning and evening adherence to inhaled therapy, control of asthma symptoms, FeNO levels, and improvement of lung function were not observed.

Conclusions:

In the in the present study reinforcement of adherence to inhaled asthma medication using short message services (SMS) via cell phones was not effective to improve adherence. Clinical Trial: None


 Citation

Please cite as:

Almonacid C, Melero C, López-Viña A, Cisneros C, Pérez-Llano L, Plaza V, García-Rivero JL, Romero MA, Ramos-González J, Bazús T, Andres-Prado MJ, Muriel A

Effectiveness of Text Message Reminders on Adherence to Inhaled Therapy in Patients With Asthma: Prospective Multicenter Randomized Clinical Trial

JMIR Form Res 2021;5(2):e12218

DOI: 10.2196/12218

PMID: 33560235

PMCID: 7902182

Per the author's request the PDF is not available.