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Accepted for/Published in: Journal of Medical Internet Research

Date Submitted: Sep 17, 2018
Open Peer Review Period: Sep 21, 2018 - Nov 16, 2018
Date Accepted: Apr 8, 2019
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

A Digital Behavioral Weight Gain Prevention Intervention in Primary Care Practice: Cost and Cost-Effectiveness Analysis

Krishnan A, Finkelstein EA, Levine E, Foley P, Askew S, Steinberg D, Bennett GG

A Digital Behavioral Weight Gain Prevention Intervention in Primary Care Practice: Cost and Cost-Effectiveness Analysis

J Med Internet Res 2019;21(5):e12201

DOI: 10.2196/12201

PMID: 31102373

PMCID: 6543798

Weight Gain Prevention in Primary Care Practice: Cost and Cost-effectiveness Analysis

  • Anirudh Krishnan; 
  • Eric Andrew Finkelstein; 
  • Erica Levine; 
  • Perry Foley; 
  • Sandy Askew; 
  • Dori Steinberg; 
  • Gary G. Bennett

ABSTRACT

Background:

Obesity is one of the largest drivers of healthcare spending, but nearly half of the population with obesity demonstrate suboptimal readiness for weight loss treatment. Black women are disproportionately likely to have both obesity and limited weight loss readiness. However, they have been shown to be receptive to strategies that prevent weight gain.

Objective:

This work evaluates the costs and cost-effectiveness of a digital weight gain prevention intervention (Shape) for Black women. Shape consisted of adaptive telephone-based coaching by health system personnel, a tailored skills training curriculum, and patient self-monitoring delivered via a fully automated interactive voice response system.

Methods:

A cost and cost-effectiveness analysis based on a randomized clinical trial of the Shape intervention reported by Bennett et al. (2013) was conducted from the payer perspective. Costs included those of delivering the program delivery to 91 intervention participants in the trial and were summarized by program element: self-monitoring, skills training, coaching, and administration. Effectiveness was measured in quality-adjusted life years (QALYs). The primary outcome was the incremental cost per QALY of Shape relative to usual care.

Results:

Shape cost an average of $758 per participant. The base-case model, in which quality of life benefits decay linearly to zero five years post intervention cessation, generated an incremental cost-effectiveness ratio (ICER) of $55,264/QALY. Probabilistic sensitivity analyses suggest an ICER below $50,000/QALY and $100,000/QALY in 39% and 98% of simulations, respectively. Results are highly sensitive to durability of benefits, rising to $165,730 if benefits end 6 months post intervention.

Conclusions:

Results suggest the Shape intervention is cost effective based on established benchmarks, indicating it can be part of a successful strategy to address the nation’s growing obesity epidemic in low-income at-risk communities. Clinical Trial: The trial was registered with the ClinicalTrials.gov database (NCT00938535, http://clinicaltrials.gov/ct2/show/NCT00938535)


 Citation

Please cite as:

Krishnan A, Finkelstein EA, Levine E, Foley P, Askew S, Steinberg D, Bennett GG

A Digital Behavioral Weight Gain Prevention Intervention in Primary Care Practice: Cost and Cost-Effectiveness Analysis

J Med Internet Res 2019;21(5):e12201

DOI: 10.2196/12201

PMID: 31102373

PMCID: 6543798

Per the author's request the PDF is not available.

© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.