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Accepted for/Published in: JMIR Public Health and Surveillance

Date Submitted: Aug 2, 2018
Date Accepted: Jun 18, 2019

The final, peer-reviewed published version of this preprint can be found here:

Flucast: A Real-Time Tool to Predict Severity of an Influenza Season

Moa A, Muscatello D, Chughtai A, Chen X, MacIntyre CR

Flucast: A Real-Time Tool to Predict Severity of an Influenza Season

JMIR Public Health Surveill 2019;5(3):e11780

DOI: 10.2196/11780

PMID: 31339102

PMCID: 6683655

Flucast: a real-time tool to predict severity of an influenza season

  • Aye Moa; 
  • David Muscatello; 
  • Abrar Chughtai; 
  • Xin Chen; 
  • C Raina MacIntyre

ABSTRACT

Background:

Influenza causes serious illness requiring annual health system surge capacity, yet annual seasonal variation makes it difficult to forecast and plan for the severity of an upcoming season. Research shows that hospital and health system stakeholders indicated a preference of forecasting tools that are easy to use and understand, to assist with surge capacity planning for influenza.

Objective:

This study aimed to develop a simple risk prediction tool, Flucast, to predict the severity of an emerging influenza season.

Methods:

Study data were obtained from the National Notifiable Diseases Surveillance System and Australian Influenza Surveillance Reports, Department of Health, Australia. We tested Flucast using retrospective seasonal data for eleven Australian influenza seasons. We compared five different models, using parameters known early in the season and which may be associated with the severity of the season. To calibrate the tool, the resulting estimates of seasonal severity were validated against independent reports of influenza-attributable morbidity and mortality. A model with highest predictive accuracy against retrospective seasonal activity was chosen as a best fit model to develop the Flucast tool. The tool was prospectively tested against the emerging 2018 influenza season.

Results:

The Flucast tool predicted the severity of all retrospectively studied years correctly for influenza seasonal activity in Australia. For 2018, the tool provided a reliable early prediction of severe seasonal influenza with the use of real-time data. The tool meets stakeholder preferences for simplicity and ease of use to assist with surge capacity planning.

Conclusions:

The Flucast tool may be useful to inform future health system influenza preparedness planning, surge capacity and intervention programs in real time and can be adapted for different settings and geographic locations. Clinical Trial: NA


 Citation

Please cite as:

Moa A, Muscatello D, Chughtai A, Chen X, MacIntyre CR

Flucast: A Real-Time Tool to Predict Severity of an Influenza Season

JMIR Public Health Surveill 2019;5(3):e11780

DOI: 10.2196/11780

PMID: 31339102

PMCID: 6683655

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