Explore our sister journals here.

Maintenance Notice

Due to necessary scheduled maintenance, the JMIR Publications website will be unavailable from Wednesday, July 01, 2020 at 8:00 PM to 10:00 PM EST. We apologize in advance for any inconvenience this may cause you.

Who will be affected?

Accepted for/Published in: JMIR Research Protocols

Date Submitted: Jun 1, 2018
Open Peer Review Period: Jun 8, 2018 - Jun 22, 2018
Date Accepted: Sep 14, 2018
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Adolescent Medicine Trials Network for HIV/AIDS Interventions Data Harmonization: Rationale and Development of Guidelines

McCumber M, Cain D, LeGrand S, Mayer KH, Murphy DA, Psioda MA, Seña AC, Starks TJ, Hudgens M

Adolescent Medicine Trials Network for HIV/AIDS Interventions Data Harmonization: Rationale and Development of Guidelines

JMIR Res Protoc 2018;7(12):e11207

DOI: 10.2196/11207

PMID: 30578242

PMCID: 6320398

Adolescent Medicine Trials Network for HIV/AIDS Interventions Data Harmonization: Rationale and Development of Guidelines

  • Micah McCumber; 
  • Demetria Cain; 
  • Sara LeGrand; 
  • Kenneth H Mayer; 
  • Debra A Murphy; 
  • Matthew A Psioda; 
  • Arlene C Seña; 
  • Tyrel J Starks; 
  • Michael Hudgens

ABSTRACT

Background:

The Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) research program aims to defeat the rising HIV epidemic among adolescents and young adults in the United States.

Objective:

This study aims to optimize cross-study analyses and comparisons of standardized measures (variables) collected in the ATN.

Methods:

Guidelines were developed for harmonizing measures to be collected across ATN studies.

Results:

Eight domains were identified for harmonization—Demographics and Socioeconomic Characteristics, Sexual Behavior and Risk, Substance Use and Abuse, HIV-Positive Cascade, HIV-Negative Cascade, Mental Health, Social Support and Isolation, and Pre-exposure Prophylaxis Cascade.

Conclusions:

The collection of selected key measures in a uniform manner across studies facilitates the characterization of participant populations, comparisons between studies, and pooled analysis of data from multiple studies.


 Citation

Please cite as:

McCumber M, Cain D, LeGrand S, Mayer KH, Murphy DA, Psioda MA, Seña AC, Starks TJ, Hudgens M

Adolescent Medicine Trials Network for HIV/AIDS Interventions Data Harmonization: Rationale and Development of Guidelines

JMIR Res Protoc 2018;7(12):e11207

DOI: 10.2196/11207

PMID: 30578242

PMCID: 6320398

Per the author's request the PDF is not available.

© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.