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Accepted for/Published in: JMIR Research Protocols

Date Submitted: May 17, 2018
Open Peer Review Period: May 22, 2018 - Jul 18, 2018
Date Accepted: Jul 18, 2018
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Hispanic Secondary Stroke Prevention Initiative Design: Study Protocol and Rationale for a Randomized Controlled Trial

Carrasquillo O, Young B, Dang S, Fontan O, Ferras N, Romano JG, Dong C, Kenya S

Hispanic Secondary Stroke Prevention Initiative Design: Study Protocol and Rationale for a Randomized Controlled Trial

JMIR Res Protoc 2018;7(10):e11083

DOI: 10.2196/11083

PMID: 30341050

PMCID: 6231896

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Hispanic Secondary Stroke Prevention Initiative Design: Study Protocol and Rationale for a Randomized Controlled Trial

  • Olveen Carrasquillo; 
  • BreAnne Young; 
  • Stuti Dang; 
  • Orieta Fontan; 
  • Natalie Ferras; 
  • Jose G Romano; 
  • Chuanhui Dong; 
  • Sonjia Kenya

Background:

Hispanic-Latino populations face a disproportionate stroke burden and are less likely to have sufficient control over stroke risk factors in comparison with other ethnic populations. A promising approach to improving chronic health outcomes has been the use of community health workers (CHWs).

Objective:

The objective of this randomized controlled trial is to evaluate the effectiveness of a CHW intervention among Latino patients at risk of recurrent stroke.

Methods:

The Hispanic Secondary Stroke Prevention Initiative (HiSSPI) is a randomized clinical trial of 300 Latino participants from South Florida who have experienced a stroke within the last 5 years. Participants randomized into the CHW intervention arm receive health education and assistance with health care navigation and social services through home visits and phone calls. The intervention also includes a mHealth component in which participants also receive daily text messages (short message service). The primary outcome is change in systolic blood pressure at 12 months. Other secondary outcomes include changes in low-density lipoprotein, glycated hemoglobin, and medication adherence.

Results:

Study enrollment began in 2015 and will be completed by the end of 2018. The first results are expected to be submitted for publication in 2020.

Conclusions:

HiSSPI is one of the first randomized controlled trials to examine CHW-facilitated stroke prevention and will provide rigorous evidence on the impact of CHWs on secondary stroke risk factors among Latino individuals who have had a stroke.

ClinicalTrial:

ClinicalTrials.gov NCT02251834; https://clinicaltrials.gov/ct2/show/NCT02251834 (Archived by WebCite at http://www.webcitation.org/72DgMqftq)

International Registered Report:

RR1-10.2196/11083


 Citation

Please cite as:

Carrasquillo O, Young B, Dang S, Fontan O, Ferras N, Romano JG, Dong C, Kenya S

Hispanic Secondary Stroke Prevention Initiative Design: Study Protocol and Rationale for a Randomized Controlled Trial

JMIR Res Protoc 2018;7(10):e11083

DOI: 10.2196/11083

PMID: 30341050

PMCID: 6231896

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