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Accepted for/Published in: JMIR Mental Health

Date Submitted: May 4, 2018
Open Peer Review Period: May 9, 2018 - Jul 4, 2018
Date Accepted: Dec 30, 2018
(closed for review but you can still tweet)

The final, peer-reviewed published version of this preprint can be found here:

Economic Evaluation of an Internet-Based Stress Management Intervention Alongside a Randomized Controlled Trial

Kählke F, Buntrock C, Smit F, Berking M, Lehr D, Heber E, Funk B, Riper H, Ebert DD

Economic Evaluation of an Internet-Based Stress Management Intervention Alongside a Randomized Controlled Trial

JMIR Ment Health 2019;6(5):e10866

DOI: 10.2196/10866

PMID: 31094355

PMCID: 6707573

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Economic Evaluation of an Internet-Based Stress Management Intervention Alongside a Randomized Controlled Trial

  • Fanny Kählke; 
  • Claudia Buntrock; 
  • Filip Smit; 
  • Matthias Berking; 
  • Dirk Lehr; 
  • Elena Heber; 
  • Burkhardt Funk; 
  • Heleen Riper; 
  • David Daniel Ebert

Background:

Work-related stress is widespread among employees and associated with high costs for German society. Internet-based stress management interventions (iSMIs) are effective in reducing such stress. However, evidence for their cost-effectiveness is scant.

Objective:

The aim of this study was to assess the cost-effectiveness of a guided iSMI for employees.

Methods:

A sample of 264 employees with elevated symptoms of perceived stress (Perceived Stress Scale≥22) was assigned to either the iSMI or a waitlist control condition (WLC) with unrestricted access to treatment as usual. Participants were recruited in Germany in 2013 and followed through 2014, and data were analyzed in 2017. The iSMI consisted of 7 sessions plus 1 booster session. It was based on problem-solving therapy and emotion regulation techniques. Costs were measured from the societal perspective, including all direct and indirect medical costs. We performed a cost-effectiveness analysis and a cost-utility analysis relating costs to a symptom-free person and quality-adjusted life years (QALYs) gained, respectively. Sampling uncertainty was handled using nonparametric bootstrapping (N=5000).

Results:

When the society is not willing to pay anything to get an additional symptom-free person (eg, willingness-to-pay [WTP]=€0), there was a 70% probability that the intervention is more cost-effective than WLC. This probability rose to 85% and 93% when the society is willing to pay €1000 and €2000, respectively, for achieving an additional symptom-free person. The cost-utility analysis yielded a 76% probability that the intervention is more cost-effective than WLC at a conservative WTP threshold of €20,000 (US $25,800) per QALY gained.

Conclusions:

Offering an iSMI to stressed employees has an acceptable likelihood of being cost-effective compared with WLC.

ClinicalTrial:

German Clinical Trials Register DRKS00004749; https://www.drks.de/DRKS00004749

International Registered Report:

RR2-10.1186/1471-2458-13-655


 Citation

Please cite as:

Kählke F, Buntrock C, Smit F, Berking M, Lehr D, Heber E, Funk B, Riper H, Ebert DD

Economic Evaluation of an Internet-Based Stress Management Intervention Alongside a Randomized Controlled Trial

JMIR Ment Health 2019;6(5):e10866

DOI: 10.2196/10866

PMID: 31094355

PMCID: 6707573

Per the author's request the PDF is not available.

© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.