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Currently submitted to: Online Journal of Public Health Informatics

Date Submitted: Jul 30, 2026
Open Peer Review Period: Aug 10, 2026 - Oct 5, 2026
(currently open for review)

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Severe obesity with fewer comorbidities is more prevalent in older Japanese women than in older Japanese men: Novel findings from the K7Ps Study-9

  • Kei Nakajima; 
  • Airi Sekine

ABSTRACT

This study investigated sex- and age-related differences in severe obesity among 9 million Japanese adults aged 40–74 years using the National Database of Health Insurance Claims and Specific Health Checkups. Overall, obesity, severe obesity, and class 3 obesity were more common in men than in women. However, after age stratification, women aged ≥ 60 years showed a higher prevalence of severe obesity and women aged 70–74 years had a higher prevalence of obesity than men of the same age. Despite their higher prevalence of severe obesity, older women had lower waist circumference, serum triglyceride and HbA1c levels, lower usage of medications for hypertension and diabetes, and a lower prevalence of cardiovascular disease than older men. These findings suggest that severe obesity accompanied by fewer cardiometabolic comorbidities is more common in older Japanese women than in older Japanese men. This unique phenotype might partly contribute to the exceptional longevity of Japanese women and warrants further investigation in populations aged 75 years and older.


 Citation

Please cite as:

Nakajima K, Sekine A

Severe obesity with fewer comorbidities is more prevalent in older Japanese women than in older Japanese men: Novel findings from the K7Ps Study-9

JMIR Preprints. 30/07/2026:108298

DOI: 10.2196/preprints.108298

URL: https://preprints.jmir.org/preprint/108298

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