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Currently accepted at: Journal of Medical Internet Research

Date Submitted: Jun 19, 2026
Open Peer Review Period: Jun 22, 2026 - Aug 17, 2026
Date Accepted: Oct 28, 2026
(closed for review but you can still tweet)

This paper has been accepted and is currently in production.

It will appear shortly on 10.2196/105075

The final accepted version (not copyedited yet) is in this tab.

Effectiveness of Web-Based Mindfulness Interventions for Mental Health Outcomes in Healthcare Professionals: A Systematic Review and Meta-Analysis

  • Moien AB Khan; 
  • Abeer AlTeneiji; 
  • Lolowa Mukhaini; 
  • Hiba Adam; 
  • Alexander Kieu; 
  • Imran Rangraze; 
  • Sohrab Amiri

ABSTRACT

Background:

Healthcare professionals are at increased risk of stress, anxiety, depression, and burnout. Web-based mindfulness interventions have emerged as accessible and scalable approaches to support mental health in this population.

Objective:

To evaluate the effectiveness of web-based mindfulness interventions on mental health outcomes among healthcare professionals.

Methods:

A systematic review and meta-analysis of randomized controlled trials published in English up to January 2026 was conducted. Searches were performed across major electronic databases. Effect sizes were calculated using Hedges’ g and pooled using random-effects models. Heterogeneity was assessed using the Q statistic and I² index. Analyses were performed using Comprehensive Meta-Analysis version 3.

Results:

Twenty-two randomized controlled trials met the inclusion criteria. Web-based mindfulness interventions were associated with significant reductions in depression (Hedges’ g = −0.35, 95% CI −0.54 to −0.16), anxiety (Hedges’ g = −0.30, 95% CI −0.41 to −0.19), and stress (Hedges’ g = −0.43, 95% CI −0.64 to −0.23). In addition, significant improvements in well-being were observed. Effects on burnout and resilience were not statistically significant.

Conclusions:

Web-based mindfulness interventions are effective in reducing depression, anxiety, and stress while improving well-being among healthcare professionals. These findings support the integration of scalable digital mindfulness programs into occupational health and workforce well-being strategies.


 Citation

Please cite as:

Khan MA, AlTeneiji A, Mukhaini L, Adam H, Kieu A, Rangraze I, Amiri S

Effectiveness of Web-Based Mindfulness Interventions for Mental Health Outcomes in Healthcare Professionals: A Systematic Review and Meta-Analysis

Journal of Medical Internet Research. 28/10/2026:105075 (forthcoming/in press)

DOI: 10.2196/105075

URL: https://preprints.jmir.org/preprint/105075

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