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Currently submitted to: JMIR Research Protocols

Date Submitted: Jul 7, 2026

Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.

Impact of malathion on pregnant women and newborns in Mexico and Latin America: a scoping review protocol

  • Rigoberto Antonio Cisneros Garcia; 
  • Felipe de Jesús Lozano Kasten; 
  • Igor Martín Ramos Herrera; 
  • Ana Karina García Suarez; 
  • Norma Guadalupe Ruiz Velazco Sandoval; 
  • Horacio Guzmán Torres; 
  • Larissa María Gómez Ruiz; 
  • Daniel Flores Rodríguez; 
  • Alejandro Aarón Peregrina Lucano

ABSTRACT

Background:

The use of organophosphorus pesticides such as malathion is common in agricultural and public health activities in Latin America. However, there is a significant gap in exposure monitoring and regulation, especially in biologically vulnerable populations such as pregnant women and newborns.

Objective:

To map and synthesize the available scientific evidence on malathion exposure and its effects on the health of the maternal-fetal dyad in Mexico and Latin America.

Methods:

A scoping review will be conducted following the Joanna Briggs Institute guidelines and the PRISMA-ScR framework. The population of interest includes pregnant women and newborns exposed to malathion in the Latin American context, under the Population, Concept, and Context (PCC) scheme. An exhaustive search will be performed in databases such as PubMed, Scopus, Web of Science, SciELO, and grey literature. Data selection and extraction will be carried out by four independent reviewers.

Results:

A narrative synthesis will be presented characterizing exposure assessment methods, reported health outcomes, and geographical and methodological gaps in regional research.

Conclusions:

The findings will aim to inform decision-makers to strengthen pesticide regulation policies and protect public health in the region.


 Citation

Please cite as:

Cisneros Garcia RA, Lozano Kasten FdJ, Ramos Herrera IM, García Suarez AK, Ruiz Velazco Sandoval NG, Guzmán Torres H, Gómez Ruiz LM, Flores Rodríguez D, Peregrina Lucano AA

Impact of malathion on pregnant women and newborns in Mexico and Latin America: a scoping review protocol

JMIR Preprints. 07/07/2026:102536

DOI: 10.2196/preprints.102536

URL: https://preprints.jmir.org/preprint/102536

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